A webinar on “Non-animal Approaches for Inhalation Toxicity Testing” will be presented on January 22, 2019, from 1:00 to 2:30 p.m. Eastern Standard Time. The webinar is organized by NICEATM on behalf of ICCVAM. The webinar is free and open to the public, but registration is required to attend. The preliminary agenda and additional information about presentations will be posted at https://ntp.niehs.nih.gov/go/commprac-2019 when available.

ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods. To address these goals, ICCVAM holds annual Communities of Practice webinars that focus on current topics in alternative methods for toxicity testing.

The upcoming webinar will provide an overview of several ongoing collaborative efforts associated with acute and subchronic inhalation toxicity testing, with emphasis on available human cell-based and in silico methodologies, dosimetry, and developing technologies that could provide predictive test methods in the future. The webinar will also present a case study describing a source-to-outcome approach that uses in vitro and in silico methods to refine inhalation risk assessment for point of contact toxicity.