At a September 18 public meeting, the U.S. Food and Drug Administration (FDA) presented an update on activities to implement its Predictive Toxicology Roadmap. Speakers from seven FDA centers described how predictive toxicology methods are being advanced towards application to safety and risk assessments. Recordings of the meeting webcast are available on the FDA website at https://www.fda.gov/science-research/about-science-research-fda/fdas-predictive-toxicology-roadmap.