The Health and Safety Environmental Institute (HESI) is seeking proposals for studies to develop human-relevant, mechanism-based assays evaluating cardiac safety liabilities. Assays should focus on any of six failure modes:
- Changes in blood pressure or heart rate
- Changes in contractility and ejection fraction
- Cardiac cell injury
- Valvular injury or proliferation
- Hemorrhage and coagulation
Awards of up to $50,000 will be awarded for 12-month projects. Awardees must be based in the United States. Letters of intent are due June 8. More information is available at https://hesiglobal.org/cardiac-safety-technical-committee/.