The third World Congress on Alternatives and Animal Use in the Life Sciences (Bologna,1999) discussed Good Cell Culture Practice (GCCP), i.e., the challenges in the performance of reliable in vitro studies using cells and tissues, which led to the Bologna declaration on GCCP. The European Centre for the Validation of Alternative Methods (ECVAM) of the European Commission then established a taskforce to generate a GCCP guidance document that would address the key principles required to assure reproducibility and quality of in vitro (cell-based) assays in 2002 and 2005. The GCCP document formed a major basis for a GLP advisory document for in vitro studies published by the OECD in 2005.
Under the leadership of CAAT, two workshops were held in 2015 in Baltimore, USA, and Konstanz, Germany, as part of the transatlantic think tank for toxicology (t4) (doi:10.14573/altex.1607121; doi:10.14573/altex.1710081). These workshop reports were utilized by a CAAT-initiated expert drafting group to produce a revised version of GCCP called GCCP 2.0, which is available now  (doi:10.14573/altex.2007091s) as supplement to the article just published in ALTEX to initiate an open public consultation prior to final publication. Over the last few years, a Scientific Advisory Committee (SAC GCCP 2.0) has been formed. All interested stakeholders are invited to join the SAC. Applicants can apply immediately and are expected to be bona fide cell culture practitioners. Please send an email to: caat@jhu.edu For more information about the SAC go to doi:10.14573/altex.2007091
All members of the SAC will have the opportunity to suggest revisions of the text, starting in September 2020 and ending November 2020.