ALTEX and the OECD have signed a memorandum of understanding on on co-operative activities in the field of adverse outcome pathway (AOP) development aiming to increase the number of AOPs developed, reviewed and published. ALTEX joins Environmental Toxicology and Chemistry and Environmental and Molecular Mutagenesis in signing a MOU with the OECD in this initiative.

ALTEX will coordinate the review of adverse outcome pathways submitted to the AOP-Wiki and publish manuscripts generated within this process as AOP Reports. An AOP Report in ALTEX provides an overview of an AOP description, which conforms with AOP development principles described in the Developers' Handbook and has been entered into the AOP-Wiki (, and describes its 3R relevance and potential application. Instructions for authors on submitting AOP Reports can be found on the ALTEX website.