Respondent ID,Start Date,End Date,What best describes your field? Select all that apply.,,,,,,,,,,,,,,,,,,,,,In which sector do you work?,,,,,,What is your gender?,,In what country do you primarily work?,What is your highest earned degree?,,,,How many years has it been since you received your highest earned degree?,How many peer-reviewed publications do you have?,"Do you regularly use animal or nonanimal models, samples, data, or materials in your research? Select all that apply.",,,,,,,,,,,,,,,,What kind of model(s) do you regularly use in your research? Select all that apply.,,,,,,,,How often do you perform animal-based experiments?,"How often do you perform animal-based experiments for the sole purpose of anticipating reviewer requests for them (i.e., you did not think the experiments were necessary outside of the context of review)?","During manuscript submission peer review, how many times have you been asked for animal experimental data to be added to a study that otherwise had no animal-based experiments?",Did you feel the requested additional animal-based experiments were justified?,Please elaborate on your answer to the previous question.,Did you comply with the request(s)?,Please elaborate on your answer to the previous question.,"When you complied with the request(s), did members of your own lab or the labs of coauthors perform additional experiments, or did you and coauthors bring in additional collaborators?",,Please elaborate on your answer to the previous question.,Have you ever had a manuscript rejected because you did not comply with a request for animal experimental data to be added to a study that otherwise had no animal-based experiments?,Please elaborate on your response to the previous question.,"During manuscript submission peer review, how often have you been asked for additional nonanimal-based experimental data to be added to a study that had no animal-based experiments? *","During manuscript submission peer review, how often have you been asked for nonanimal-based experimental data to be added to a study that had animal-based experiments? *","During manuscript submission peer review, how often have you been asked for additional animal-based experimental data to be added to a study that had animal-based experiments?",Are there any additional details you would like to share about your experience(s) during manuscript review being asked for additional experimental data?,How often do you serve as a manuscript reviewer for scientific journals? *,"In your capacity as a reviewer for a scientific journal, how often do you request animal experimental data to be added to a study that otherwise had no animal-based experiments?",For what reasons have you requested that animal-based experimental data be added to a study that otherwise had no animal experiments?,,,,,Please elaborate on your response to the previous question.,"In your capacity as a reviewer for a scientific journal, how often do you request nonanimal-based experimental data to be added to a study that had animal-based experiments?","In your capacity as a reviewer for a scientific journal, how often do you request nonanimal-based experimental data to be added to a study that had no animal-based experiments?","In your capacity as a reviewer for a scientific journal, how often do you request animal-based experimental data to be added to a study that had animal-based experiments?",Are there any additional details you would like to share about your experience(s) as a reviewer requesting additional data?
,,,Anthropology,Biochemistry and biophysics,Biotechnology,Computational biology,Disease research,Ecology,Environmental sciences,Evolutionary biology,Genetics and genomics,Health disparities,Medicine and clinical research,Microbiology,Molecular and cellular biology,Neuroscience,Nutritional sciences,Pharmacology,Physiology,Social sciences,Systems biology,Toxicology,Other (please specify),Academia/Research institution,Industry,Government,Nonprofit/NGO,Publishing,Other (please specify),Response,Prefer to self-describe,Response,Master's degree,Research doctorate (e.g. PhD),"Medical degree (e.g. MD, DDS)",Other (please specify),Response,Response,Animal-based - Models,Animal-based - Samples,Animal-based - Data,Animal-based - Materials,Animal-based - None,Nonanimal-based - Models,Nonanimal-based - Samples,Nonanimal-based - Data,Nonanimal-based - Materials,Nonanimal-based - None,Other (please specify below) - Models,Other (please specify below) - Samples,Other (please specify below) - Data,Other (please specify below) - Materials,Other (please specify below) - None,Other (please specify),2D cell culture,Biopsies,Computational,Live organisms,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",Post-mortem tissue,Other (please specify),Response,Response,Response,Response,Open-Ended Response,Response,Open-Ended Response,Response,Other (please specify),Open-Ended Response,Response,Open-Ended Response,Response,Response,Response,Open-Ended Response,Response,Response,Journal policy,Request from editor,Preference for animal-based methods,Unaware of nonanimal or alternative methods for the given hypothesis,Other (please specify),Open-Ended Response,Response,Response,Response,Open-Ended Response
12895147395,8/16/2021 3:51,8/16/2021 3:59,,,,,,,,,,,,,,,,,,,,,Dentistry and Dental Biomaterials,Academia/Research institution,,,,,,Male,,"Korea, South",Master's degree,Research doctorate (e.g. PhD),"Medical degree (e.g. MD, DDS)",,10-Jun,41-100,Models,Samples,Data,Materials,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,,,,,"Organoids, spheroids",,Organotypic model (3d cultured full tissue like EpiSkin model),Rarely,Sometimes,5-Jan,Sometimes,Some of evidences are lacking with in vitro experiments (lack of previous research data linking to clinical data),No,"With limited time/money along with ethical concern, request was rejected and paper was withdrawn.",,,,Sometimes,"Not by reviewer but at Editorial level. Some of papers are well known that without animal data and with only in vitro results, Editor is not willing to progress further with review",Often,Never,Rarely,,At least once per month,Never,,,,,,,Less than once per year,At least once per month,Never,
12882548790,8/10/2021 16:29,8/10/2021 16:33,,,,,,,,,,,Medicine and clinical research,,Molecular and cellular biology,,,,,,,,,,Industry,,,,,Female,,"Korea, South",,Research doctorate (e.g. PhD),,,20-Nov,20-Nov,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12881562346,8/10/2021 9:42,8/10/2021 9:50,,,,,Disease research,,,,,,Medicine and clinical research,,Molecular and cellular biology,,,,Physiology,,,Toxicology,,Academia/Research institution,,,,,,Male,,"Korea, South",,Research doctorate (e.g. PhD),"Medical degree (e.g. MD, DDS)",,20-Nov,41-100,,,,,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,Biopsies,,,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",,,Rarely,Never,0,,,,,,,,,,Never,Never,Never,N/A,At least once per month,Never,,,,,,,Never,Never,Never,N/A
12880653875,8/10/2021 4:59,8/10/2021 5:02,,,,,,,,,,,,,,,,,,,,Toxicology,,Academia/Research institution,,,,,,Male,,"Korea, South",,Research doctorate (e.g. PhD),,,10-Jun,41-100,,Samples,,,,Models,Samples,Data,Materials,,,,,,,,,,,,,"Organoids, spheroids",,,Rarely,Sometimes,5-Jan,,,,,,,,,,,,,,,,,,,,,,,,,
12880279258,8/10/2021 1:06,8/10/2021 2:20,,,,,,,,,,,,,,,,,Physiology,,,Toxicology,,Academia/Research institution,,,,,,Prefer not to say,,"Korea, South",,Research doctorate (e.g. PhD),,VMD,10-Jun,>100,Models,Samples,Data,,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,,,Live organisms,,"Organoids, spheroids",Post-mortem tissue,,Always,Rarely,10-Jun,Sometimes,"It was primarily a reasonable request to verify the efficacy of the substance. However, there were some cases where the importance was not very high for the completeness of the thesis.",Sometimes,I have responded to reasonable requests.,Own lab(s) or lab(s) of coauthors,,N/A,Not sure,"Usually, that's not only the reason.",Always,Often,Rarely,"Personally, I think it's rare cases to ask to add unreasonable or unnecessary animal data.",Several times per month,Less than once per year,,,,,"When I think that it is difficult to verify a hypothesis with only in vitro experiments, I request in vivo verification for systemic evaluation.","When I think that it is difficult to verify a hypothesis with only in vitro experiments, I request in vivo verification for systemic evaluation.",At least once per month,At least once per month,Less than once per year,"Since animal experiment proceeds with a lot of consideration, it is rare that indiscriminate additional experiments are required."
12880247071,8/10/2021 0:41,8/10/2021 0:54,,,Biotechnology,,,,,,,,,,,,,,,,,,,,Industry,,,,,Female,,"Korea, South",,Research doctorate (e.g. PhD),,,10-Jun,20-Nov,,,,,,Models,,,,,,,,,,,2D cell culture,,,,,,,"3D ALI Model (skin, cornea, airway..)",Never,Rarely,0,,,,,,,,,,Sometimes,Rarely,Sometimes,,At least once per year,Never,,,,,,,Less than once per year,Less than once per year,Never,
12880156318,8/9/2021 23:37,8/9/2021 23:42,,,,,,,,,,,,,,,,Pharmacology,,,,,,Academia/Research institution,,,,,,Male,,"Korea, South",,Research doctorate (e.g. PhD),,,>20,>100,,Samples,,,,,,Data,Materials,,,,,,,,,,,,,"Organoids, spheroids",,,Rarely,Rarely,5-Jan,Sometimes,IRB,No,,,,,No,,Sometimes,Sometimes,Sometimes,,At least once per month,At least once per year,,,Preference for animal-based methods,,,,At least once per year,Less than once per year,At least once per year,
12880072936,8/9/2021 22:23,8/9/2021 22:30,,,Biotechnology,,,,,,,,,,,,,Pharmacology,,,,Toxicology,,,Industry,,,,,Male,,"Korea, South",Master's degree,,,,10-Jun,10-Jan,Models,,,,,,,Data,,,Models,,,,,,2D cell culture,,,,,,,,Often,Often,10-Jun,Yes,,No,,,,,No,,Rarely,Rarely,Sometimes,,Less than once per year,At least once per year,,Request from editor,,,,,Less than once per year,At least once per year,At least once per month,
12879989674,8/9/2021 20:55,8/9/2021 21:20,,,Biotechnology,,,,,,,,,,,,,,,,,,,,,,,Publishing,,Female,,"Korea, South",,Research doctorate (e.g. PhD),,,>20,10-Jan,,,,,,,Samples,,Materials,,,,,,,,2D cell culture,Biopsies,,,,,,,Rarely,Never,0,,,,,,,,,,Sometimes,Sometimes,Sometimes,,Less than once per year,Less than once per year,,,Preference for animal-based methods,,,,Less than once per year,Never,Less than once per year,
12879798266,8/9/2021 18:33,8/9/2021 18:49,,,Biotechnology,,,,,,,,,,,,,,,,,Toxicology,,Academia/Research institution,,,,,,Female,,"Korea, South",,Research doctorate (e.g. PhD),,,10-Jun,41-100,Models,Samples,Data,Materials,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,Biopsies,Computational,Live organisms,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",,,Sometimes,Often,>20,Sometimes,,Yes,,Combination,,,Not sure,"If there are requests, we accepted all requests and did the experiments",Often,Often,Often,,At least once per year,At least once per year,,,,Unaware of nonanimal or alternative methods for the given hypothesis,,,Less than once per year,Less than once per year,Less than once per year,
12879786883,8/9/2021 18:32,8/9/2021 18:37,,,Biotechnology,,Disease research,,,,,,,,Molecular and cellular biology,,,Pharmacology,Physiology,,,,,Academia/Research institution,,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,10-Jun,21-40,,,Data,,,Models,Samples,Data,Materials,,,,,,,,,,,,"Microphysiological systems, organ chips, tissue chips",,,,Rarely,Sometimes,5-Jan,No,Animal models are seen as a way to validate in vitro data. This is ironical ,No,We submit in a different journal,,,,Yes,,Often,Never,Sometimes,,At least once per month,Never,,,,,,,N/A,At least once per year,Less than once per year,
12879767499,8/9/2021 18:19,8/9/2021 18:24,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Male,,"Korea, South",,Research doctorate (e.g. PhD),"Medical degree (e.g. MD, DDS)",,20-Nov,>100,Models,Samples,Data,Materials,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,Biopsies,Computational,,"Microphysiological systems, organ chips, tissue chips",,,,Sometimes,Sometimes,5-Jan,Sometimes,,Sometimes,,Combination,,,Sometimes,,Sometimes,Sometimes,Rarely,,At least once per year,Less than once per year,,,Preference for animal-based methods,,,,At least once per year,At least once per year,Less than once per year,
12879755135,8/9/2021 18:09,8/9/2021 18:12,,,,,,,,,,,,,,,,,,,,,Veterinary Meicine,,,,,,Private Practice,Prefer not to say,,United Kingdom,Master's degree,,,,>20,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12879326294,8/9/2021 14:24,8/9/2021 14:46,,,,,,,,,,,,,,,,Pharmacology,,,,Toxicology,,,Industry,,,,,Male,,India,Master's degree,,,MVSc (Pharmacology & Toxicology),10-Jun,10-Jan,Models,Samples,Data,Materials,,,Samples,Data,,,,,,,,,,Biopsies,Computational,,,,Post-mortem tissue,,Sometimes,Never,0,,,,,,,,,,Rarely,Never,N/A,No,At least once per year,Never,,,,,,,At least once per year,At least once per year,At least once per year,No
12872296642,8/5/2021 23:12,8/5/2021 23:26,,,,Computational biology,,,,,,,,,,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Female,,Belgium,,Research doctorate (e.g. PhD),,,20-Nov,21-40,Models,,Data,,,Models,,Data,,,,,,,,,,,Computational,,,,,,Never,Rarely,5-Jan,Sometimes,"It is not justified to ask modeler, human experimenter to replicate their findings in animal exp, because I have no lab to do this snd present plausible model simulations that support my case. I would need to set up a collaboration to get these animal data, snd thst would take additional years, in the meantime papers are not published and others cannot build upon the work. ",Sometimes,"I have pulled publications and waited for snimal labs to perform exp with my stimuli first. I gave them the support to run these exp, but am not necessarily an author on that work, and this causes massive delays in the publications from my lab",Additional collaborators,,"Ser previous, I do not have zn animal phys lab",Yes,"They did not trust the in silico predictions in z biophys realistic computational model, and wanted the animal evidence",Sometimes,N/A,N/A,No,Several times per month,Never,,,,,,,Never,At least once per year,At least once per year,No
12870360281,8/5/2021 7:07,8/5/2021 7:21,,Biochemistry and biophysics,,,,,,,,,,,,,,,,,,,,Academia/Research institution,,,,,,Male,,United Kingdom,,,"Medical degree (e.g. MD, DDS)",,10-Jun,21-40,Models,,,,,,,,,,,,,,,,,,,,,"Organoids, spheroids",,,Sometimes,Rarely,5-Jan,Yes,Some ethical and social limitations can be overcome and long term complete observation can be made,Yes,We will do a good job in protecting relevant intellectual property rights.,,,,,,,,,,,,,,,,,,,,,
12869756939,8/5/2021 2:24,8/5/2021 2:36,,Biochemistry and biophysics,,,Disease research,,,,,,Medicine and clinical research,,Molecular and cellular biology,,,Pharmacology,,,,,,Academia/Research institution,,,,,,Female,,Italy,,Research doctorate (e.g. PhD),,,20-Nov,41-100,Models,Samples,Data,,,Models,Samples,Data,,,,,,,,,2D cell culture,,,Live organisms,,,Post-mortem tissue,,Often,Never,10-Jun,Sometimes,To understand interaction beteen a tumor cell and host immune system or host cells in general or to study systemic reactions to a drug animal experiments are justified in my opinion.,Sometimes,In my early days of research i did not had access to animal models therefore I was able to comply with the requests only when establishing dedicated collaborations with colleauges,Combination,,,Not sure,,Always,Always,Sometimes,,Several times per month,At least once per year,,,,Unaware of nonanimal or alternative methods for the given hypothesis,,,Several times per month,Several times per month,At least once per month,"the type of extra experiments I request depends mainly on the focus of the study and the hypothesis the authors want to demonstrate. Therefore, I suggest animal experiments more rarely than in vitro experiments . This is also depends on the knowledge that often extra animal experiments require ethics approval and a longer time to be performed therefore they are not always compatible with the timings for resubmission allowed by the publishers. if a substantial amount of animal experiments is requested in my opinion I rather suggest rejection than revision"
12819443752,7/14/2021 11:24,7/14/2021 11:32,,,,,,,,,,,,,,,,Pharmacology,,,,,,Academia/Research institution,,,,,,Female,,Canada,,Research doctorate (e.g. PhD),,,>20,41-100,Models,Samples,Data,Materials,,Models,Samples,Data,Materials,,Models,,,,,"Computer and mathematical models (PK, PBPK)",,Biopsies,Computational,Live organisms,,"Organoids, spheroids",Post-mortem tissue,,Sometimes,Never,5-Jan,Sometimes,"Sometimes the reviewers identify critical gaps in knowledge, these are valuable peer reviews. Other times it seems like they ask for animals out of habit. We refuse. This is even more difficult and hard to deal with when it comes to grant reviews",Sometimes,Please see the answer above in 14.,Own lab(s) or lab(s) of coauthors,,"We have IACUCs in limited circumstances. If we need to do the work we do it - although replacement is important, we're not at the level of 100% replacement yet.",Sometimes,Yes a few times. We simply sent the manuscript elsewhere - we do not perform frivolous animal experiments because of a request from a reviewer unless I as PI agree that the data is critical,Often,Sometimes,Sometimes,I think you should also include grant review in this survey - in my experience reviewers on grant panels are even more likely to ask for animal experiments than manuscript reviewers,Several times per month,Never,,,,,,,At least once per month,At least once per month,Less than once per year,My main request for additional data is when controls are missing - this seems to be the most common missing thing these days - I would say it is more of a problem than it was ~20 years ago as people rush to publish
12818415777,7/14/2021 4:54,7/14/2021 4:56,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Male,,Switzerland,,Research doctorate (e.g. PhD),"Medical degree (e.g. MD, DDS)",,20-Nov,41-100,Models,Samples,Data,Materials,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,,,,,"Organoids, spheroids",,,Often,Never,0,,,,,,,,,,,,,,,,,,,,,,,,,
12813874014,7/12/2021 13:43,7/12/2021 13:45,,,,,,,,,,,,,,,,,,,Systems biology,,,,,,,,.,Female,,Italy,,,,Triennale,10-Jun,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12803138138,7/8/2021 0:59,7/8/2021 1:17,,,,,,,,,,,Medicine and clinical research,Microbiology,Molecular and cellular biology,,,,,,,,,Academia/Research institution,,,,,,Male,,Netherlands,,Research doctorate (e.g. PhD),,,20-Nov,21-40,Models,Samples,,,,,,,,,,,,,,,,Biopsies,,Live organisms,,,Post-mortem tissue,,Rarely,Never,0,,,,,,,,,,Never,Never,Never,,Several times per month,Never,,,,,,,Never,Never,Less than once per year,In some cases the original animal experiment was not conducted properly or without the right controls. Then I would make suggestions.
12800861420,7/7/2021 6:20,7/7/2021 6:23,,,,,,,,,Genetics and genomics,,,,,,,,,,,,,,Industry,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,10-Jun,20-Nov,,,,,None,,,Data,,,,,,,None,,,,Computational,,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",,,Rarely,Often,5-Jan,,,,,,,,,,,,,,,,,,,,,,,,,
12799820444,7/6/2021 21:30,7/6/2021 21:33,,,,,,,Environmental sciences,,,,,,,Neuroscience,,,,,,,,,,,,,Private practice,Female,,United States,,Research doctorate (e.g. PhD),,,>20,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12795117596,7/5/2021 3:44,7/5/2021 3:58,,,,,,,,,,,,,Molecular and cellular biology,,,,,,,,,Academia/Research institution,,,,,,Female,,United Kingdom,,Research doctorate (e.g. PhD),,,>20,21-40,,,,Materials,None,Models,Samples,,Materials,,,,,,,,2D cell culture,Biopsies,,,,"Organoids, spheroids",,,Never,Never,5-Jan,No,The study was about heterogeneity of cancer cells from human tissue samples. It was irrelevant to do an experiment on mice.,No,"Reviewer three said words to the effect of ""there are no mouse experiments in this study therefore I reject it for this journal"". They said nothing about the rest of the study. I submitted to a different journal.",,,,No,I just submitted to other journals if animal studies were requested.,Sometimes,Sometimes,Never,"The journals that wanted animal experiments were journals with higher impact factor. I submitted my work to journals with lower impact factor. Therefore it is not to hard to conclude that people who do animal experiments are perceived to be better scientists because they are allowed / encouraged to submit to those journals with higher impact factor. Self-fulfilling prophecy meaning there is no incentive to not do animal experiments. One scientist at a conference proudly announced they had used 2000 mice in one paper. I went to another seminar where the whole talk was about a virus study in primates - at the end they showed that the effect in primates was totally different to that in humans, therefore negating their entire study.  ",At least once per year,Never,,,,,,,At least once per year,At least once per year,Less than once per year,If I am asked to review a paper that is entirely based on mouse models for example I will probably not accept to review this because I don't work with mouse models myself. If there are lots of other molecular and cellular experiments with a few mouse experiments then I would accept that paper to review. 
12793603132,7/4/2021 8:19,7/4/2021 8:19,,,,,,,,,,,,,,,,,,,,,Physics,Academia/Research institution,,,,,,Male,,Germany,,Research doctorate (e.g. PhD),,,0-5,20-Nov,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12791479228,7/2/2021 16:41,7/2/2021 18:36,,,,,,,,,,Health disparities,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Male,,United States,,,"Medical degree (e.g. MD, DDS)",,10-Jun,21-40,,,,,None,Models,,Data,,,Models,,Data,,,,,Biopsies,,,,,,,Never,Never,0,,,,,,,,,,Never,Never,Never,,At least once per year,Never,,,,,,,,,,
12784754279,6/30/2021 8:32,6/30/2021 8:42,,,,,,,,,,,,,,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Female,,Brazil,,Research doctorate (e.g. PhD),,,>20,21-40,Models,Samples,Data,,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,,,,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",Post-mortem tissue,,Rarely,Never,5-Jan,No,"The reviewer simply claimed that the human cellular models we used were not useful models to study viral infection, implying that only animal models would be acceptable.",No,We submitted the manuscript to another journal,,,,No,,Often,Never,Sometimes,,At least once per year,Never,,,,,,,At least once per year,At least once per year,At least once per year,
12784458828,6/30/2021 6:59,6/30/2021 7:02,,,,,,,,,,,,,,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Female,,United States,,Research doctorate (e.g. PhD),,,0-5,10-Jan,Models,,Data,,,,,,,,,,,,,,,,Computational,Live organisms,,,,,Always,Never,N/A; e.g. if you've only submitted studies with animal-based experiments,,,,,,,,,,Never,Never,Sometimes,,At least once per year,Never,,,,,,,Less than once per year,At least once per year,Less than once per year,
12784391370,6/30/2021 6:35,6/30/2021 6:37,,,,,,,,,,,,,,,,,,Social sciences,,,,Academia/Research institution,,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,>20,21-40,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12783438564,6/29/2021 23:13,6/29/2021 23:15,,,,,,,,,,,,,,,,,,,,,Animal welfare,Academia/Research institution,,,,,,Female,,Germany,,Research doctorate (e.g. PhD),,,>20,41-100,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12783384804,6/29/2021 22:36,6/29/2021 22:39,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Female,,Romania,,Research doctorate (e.g. PhD),,,10-Jun,10-Jan,,Samples,Data,Materials,,Models,Samples,Data,Materials,,,,,,,,,Biopsies,,Live organisms,"Microphysiological systems, organ chips, tissue chips",,Post-mortem tissue,,Sometimes,Sometimes,5-Jan,Sometimes,Animal based models are not always the best in specific research,Sometimes,"As stated before, sometimes they were just not applicable",,,,,,,,,,,,,,,,,,,,,
12782536269,6/29/2021 15:07,6/29/2021 15:09,,,,,,,,Evolutionary biology,Genetics and genomics,,,,Molecular and cellular biology,,,,,,,,,Academia/Research institution,,,,,,Male,,Canada,,Research doctorate (e.g. PhD),,,>20,21-40,,,,,None,,,,,None,,Samples,,,,Animal DNA and RNA samples,,,,,,,,None,Sometimes,Never,N/A; e.g. if you've only submitted studies with animal-based experiments,,,,,,,,,,N/A,N/A,N/A,,,,,,,,,,,,,
12781662215,6/29/2021 9:45,6/29/2021 9:47,,,,,,,,,,,,,,,,,,Social sciences,,,,Academia/Research institution,,,,,,Male,,Denmark,,Research doctorate (e.g. PhD),,,10-Jun,20-Nov,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12781425706,6/29/2021 8:26,6/29/2021 8:43,,Biochemistry and biophysics,,,,,,,,,,,,,,,,,,,,Academia/Research institution,,,,,,Female,,Italy,,Research doctorate (e.g. PhD),,,0-5,20-Nov,,,,,None,,Samples,Data,Materials,,,,,,,,2D cell culture,,,,,"Organoids, spheroids",,,Rarely,Sometimes,5-Jan,No,"Referees ask for animal experiments because it is customary to do so in the field of biophysics, toxicology not because it is necessary. Many researchers are unaware about the potential of in vitro, in silico methods and human based models. ",Sometimes,In my group sometimes animal experiments are performed to publish on journal with high impact factor but I do not agree. I would go on employing and studying new non-animal methods,Combination,,Sometimes they are performed by the coauthors,Not sure,I know from the experience of my PI that papers not showing animal experiments are much more likely to be rejected from high impact journals,Sometimes,Rarely,Rarely,,At least once per month,Never,,,,,,,At least once per month,Less than once per year,Never,Often researcher are not aware of newly developed methods. As referee it is important to share info
12781445957,6/29/2021 8:32,6/29/2021 8:33,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Male,,Netherlands,,Research doctorate (e.g. PhD),,,0-5,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12781347915,6/29/2021 8:00,6/29/2021 8:08,,,,,,,,,,,,,Molecular and cellular biology,Neuroscience,,Pharmacology,,,,Toxicology,,Academia/Research institution,,,,,,Female,,United Kingdom,,Research doctorate (e.g. PhD),,,0-5,10-Jan,Models,,,,,Models,Samples,,Materials,,,,,,,,2D cell culture,,,,"Microphysiological systems, organ chips, tissue chips",,,,Rarely,Sometimes,5-Jan,No,The animal studied that were asked were to only emphysize the results we obtained invitro. no other reason,No,Submitted to another journal as we dont have an animal breeding facility as we comply with 3R,,,,Yes,"Yes. Had the reviewer said missing animal results. When i sent my response back that i wont do it, it was rejected ",Sometimes,Sometimes,Sometimes,,Less than once per year,Never,,,,,,,At least once per year,At least once per year,Never,
12781200709,6/29/2021 7:07,6/29/2021 7:16,,,,,,,,,,,,,,,,,,,,,Taxonomy,Academia/Research institution,,,,,,Male,,China,,Research doctorate (e.g. PhD),,,10-Jun,41-100,,Samples,Data,Materials,,,,,,None,,,,,,,,,,Live organisms,,,Post-mortem tissue,,Sometimes,Never,0,,,,,,,,,,Rarely,Rarely,Never,,At least once per month,Never,,,,,,,At least once per year,At least once per year,At least once per year,
12781109728,6/29/2021 6:40,6/29/2021 6:44,,,,,,,,,,,,,,,,,,,,,materials ,Academia/Research institution,,,,,,Female,,Greece,,Research doctorate (e.g. PhD),,,>20,21-40,Models,,,,None,Models,,,,None,,,,,,,2D cell culture,,,,,,,,Never,Never,0,,,,,,,,,,Never,Never,Never,,Several times per month,Never,,,,,,,At least once per year,At least once per year,Never,
12781100669,6/29/2021 6:37,6/29/2021 6:40,,,,,,,,,,,,,,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Female,,United States,,Research doctorate (e.g. PhD),,,10-Jun,20-Nov,,,,,None,Models,Samples,Data,Materials,,,,,,,,,,,Live organisms,,,,,Never,Never,0,,,,,,,,,,Sometimes,N/A,N/A,,At least once per year,Never,,,,,,,Never,Never,Never,
12781095470,6/29/2021 6:35,6/29/2021 6:37,,,,,,,,,,,,,,,,,,Social sciences,,,,Academia/Research institution,,,,,,Female,,Slovakia,,Research doctorate (e.g. PhD),,,0-5,20-Nov,,,,,None,,,,,None,,,,,None,,,,,,,,,none,Never,Never,N/A; e.g. if you've only submitted studies with animal-based experiments,,,,,,,,,,,,,,,,,,,,,,,,,
12781067614,6/29/2021 6:26,6/29/2021 6:33,,,,,Disease research,,,,,,,,,,,,,,,,,Academia/Research institution,,,,,,Male,,Denmark,,Research doctorate (e.g. PhD),,,10-Jun,41-100,,Samples,,Materials,,,,,,None,,,,,,Cell cultures ,2D cell culture,,,Live organisms,,,Post-mortem tissue,,Sometimes,Never,0,,,,,,,,,,Rarely,Rarely,Sometimes,,Several times per month,Less than once per year,,,,Unaware of nonanimal or alternative methods for the given hypothesis,,"Sometimes, the interaction between host and pathogens cannot be modelled at organisms levels. ",At least once per year,At least once per year,Less than once per year,
12781053332,6/29/2021 6:22,6/29/2021 6:23,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Male,,Denmark,,,"Medical degree (e.g. MD, DDS)",,0-5,10-Jan,,,,,None,Models,Samples,Data,Materials,,,,,,None,,,,Computational,Live organisms,,,,,Never,Never,0,,,,,,,,,,,,,,,,,,,,,,,,,
12781003518,6/29/2021 6:06,6/29/2021 6:09,,,,,,,,,,,Medicine and clinical research,,,,,,,Social sciences,,,,Academia/Research institution,,,,,,Male,,Poland,,Research doctorate (e.g. PhD),,,20-Nov,10-Jan,,,,,None,Models,Samples,Data,,,,,,,,,,,,Live organisms,,,,,Never,Never,N/A; e.g. if you've only submitted studies with animal-based experiments,,,,,,,,,,Never,Never,Never,,Several times per month,Never,,,,,,,Never,Never,Never,
12780999818,6/29/2021 6:05,6/29/2021 6:06,,,,,,,,,,,,,,Neuroscience,,,,,,,Psychology,Academia/Research institution,,,,,,Male,,Portugal,,Research doctorate (e.g. PhD),,,0-5,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12775376900,6/26/2021 12:34,6/26/2021 12:42,,,,,,,,,,,Medicine and clinical research,,,,Nutritional sciences,,,,,,,,,,Nonprofit/NGO,,,Male,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,None,,,,,None,,,,,None,,,,,,,,,Dietary studies on humans,Never,Never,0,,,,,,,,,,Never,N/A,N/A,,Less than once per year,Never,,,,,,,N/A,N/A,N/A,
12771251697,6/24/2021 16:00,6/24/2021 16:06,,,,,,,,,,,,,,,,,,,,,public health,,,,,,private consulting group,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,None,,Samples,Data,Materials,,,,,,,,,,,,,,,None,Never,Never,0,,,,,,,,,,Never,N/A,N/A,,Never,,,,,,,,,,,
12769801751,6/24/2021 6:56,6/24/2021 6:57,,,,,,,,,,,,,,,,,,Social sciences,,,,Academia/Research institution,,,,,,Female,,Canada,,Research doctorate (e.g. PhD),,,>20,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12768695917,6/23/2021 21:56,6/23/2021 21:58,,,,,,,,,,,,,,,,,,Social sciences,,,,,,,,Publishing,,Female,,Serbia,Master's degree,,,,>20,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12768262251,6/23/2021 17:23,6/23/2021 17:25,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Male,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12768225849,6/23/2021 17:06,6/23/2021 17:08,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,,,clinical medicine,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,20-Nov,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12767980385,6/23/2021 16:09,6/23/2021 16:10,,,,,,,,,,,,,,,,Pharmacology,,,,,,,,Government,,,,Female,,Canada,,,,DVM,20-Nov,10-Jan,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12767810872,6/23/2021 15:22,6/23/2021 15:25,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,41-100,,,,,None,,,,,None,,,,,None,,,,,,,,,none---only human,Never,Never,0,,,,,,,,,,Never,Never,Never,,At least once per year,Never,,,,,,,Never,Never,Never,i am an epidemiologist
12767731445,6/23/2021 14:56,6/23/2021 14:57,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,Nonprofit/NGO,,,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12767589207,6/23/2021 14:02,6/23/2021 14:15,,,,,,,,,,,,Microbiology,,,,,,,,,,Academia/Research institution,,,,,,Male,,Ecuador,,Research doctorate (e.g. PhD),,,20-Nov,20-Nov,,,Data,Materials,,,Samples,Data,,,Models,,Data,Materials,,"Samples from fungi or bacteria, which are also models. I also used fruit flies and moth larvae in one ocassion.",,,,Live organisms,,,,,Never,Never,0,,,,,,,,,,Never,Never,Never,"I don't remember being asked to perform experiments on animal models when I was not the principal investigator of the projects, but it is possible that the principal investigator decided to do experiments on animals just because it was the normal thing to do.",At least once per year,Never,,,,,,,N/A,N/A,N/A,"I still didn't have to ask for additional experiments to improve a manuscript, I don't have that much experience being both principal investigator or reviewer. I don't like animal experiments and consider most of them unnecessary, so it is very unlikely that I would request additional experiments with animals for a publication."
12767618817,6/23/2021 14:13,6/23/2021 14:15,,,,,,,,,,,,,,,,,,,,,Dentist,,,,,,Retired from private practice,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12767445870,6/23/2021 13:02,6/23/2021 13:13,,,,,,,,,,,,,,,,,,Social sciences,,,,,,Government,,,,Male,,United States,,Research doctorate (e.g. PhD),,,>20,10-Jan,,,,,None,,,Data,,,,,,,,,,,,,,,,I am a retired U.S. diplomat with ewo published books and a number of articles including published speeches ,Never,Never,0,,,,,,,,,,Never,Never,Never,"In the USG one is required to obtain ""clearances"" to advance a document",Never,,,,,,,,,,,
12767221817,6/23/2021 11:34,6/23/2021 11:37,,,,,,,,,,,,,,,,,,,,,Diagnostic Radiology,,,,,,Private sactor,Male,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,None,,,,,None,,,,,None,,,,,,,,,none,Never,Never,0,,,,,,,,,,,,,,,,,,,,,,,,,
12767072019,6/23/2021 10:41,6/23/2021 10:51,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,Academia/Research institution,,,,,,Female,,United Kingdom,,Research doctorate (e.g. PhD),,,20-Nov,21-40,,,,,None,,,Data,Materials,,,,,,,,,Biopsies,,,,,Post-mortem tissue,,Never,Never,0,,,,,,,,,,Rarely,Sometimes,N/A,"I have been asked several times to peer review animal-based studies. I have always declined. I work in perinatal neurology and obtain my data mainly from imaging (MRI, ultrasound). I have seen animal-based studies where a brain injury was caused to an animal (during gestation or first few postnatal days) with the aim to show the pattern of injury or developmental consequences. Most of the data are already known from human studies. I have always written to editors explaining why they should not accept this kind of manuscripts; I have never received a response. The number of manuscripts submitted with these animal data is still huge. ",At least once per month,Never,,,,,,,N/A,Less than once per year,N/A,I never peer review animal-based studies. I have always refused. 
12767089272,6/23/2021 10:47,6/23/2021 10:48,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,,,retired,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12767072923,6/23/2021 10:40,6/23/2021 10:47,,,,,,,,,,,,,,,,,,,,,Organic Chemistry,Academia/Research institution,,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,>20,10-Jan,,,,,None,Models,Samples,Data,Materials,,,,,,,,,,Computational,,,,,,Never,Never,0,,,,,,,,,,Never,N/A,N/A,No,Never,,,,,,,,,,,
12767043620,6/23/2021 10:30,6/23/2021 10:33,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,,,Private hospital ,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,None,,,,,None,,,,,,,,Biopsies,,,,,,,Never,Never,0,,,,,,,,,,Never,Never,Never,,Never,,,,,,,,,,,
12767005230,6/23/2021 10:17,6/23/2021 10:23,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,Industry,,,,,Male,,United States,,Research doctorate (e.g. PhD),"Medical degree (e.g. MD, DDS)",,>20,>100,,,,,None,Models,,,,,,,,,None,,,Biopsies,,,,,,patients samples,Never,Never,0,,,,,,,,,,Sometimes,N/A,Never, na,Several times per month,Never,,,,,,,At least once per year,Less than once per year,Never,No
12766995826,6/23/2021 10:14,6/23/2021 10:18,,,,,,,,,,,Medicine and clinical research,,,,Nutritional sciences,,,,,,,Academia/Research institution,,,,,,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,20-Nov,Models,Samples,,Materials,,,,,,,,,,,,,2D cell culture,,,,,"Organoids, spheroids",Post-mortem tissue,,Sometimes,Never,0,,,,,,,,,,Often,Often,Rarely,My prior research required tissue culture or cell based assays as a major focus of study.,Less than once per year,Never,,,,,,,Less than once per year,Less than once per year,Never,
12766967680,6/23/2021 10:01,6/23/2021 10:08,,,,,,,,,,,,,,,,,,,,,Medical Devicde Standards,,,,Nonprofit/NGO,,,Male,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,None,,,,,None,,,,,,,,,,,,,,No Models,Never,Never,0,,,,,,,,,,Never,Never,Never,,Never,,,,,,,,,,,
12766971961,6/23/2021 10:05,6/23/2021 10:07,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,,,medical practice,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12766942023,6/23/2021 9:55,6/23/2021 10:04,,,,,,,,,,,,,,,Nutritional sciences,,,,,,,Academia/Research institution,,,,,,Male,,Iraq,,Research doctorate (e.g. PhD),,,0-5,10-Jan,,,,,None,,,,,None,,,,,None,,,,,,,,Post-mortem tissue,,Never,Never,0,,,,,,,,,,Rarely,Rarely,Never,no,Less than once per year,Never,,,,,,,Never,Never,N/A,food science and food processing
12766919214,6/23/2021 9:47,6/23/2021 9:52,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,Nonprofit/NGO,,,Male,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,41-100,,,,,None,,,,,None,,,,,,I don't conduct preclinical research,,,,,,,,None,Never,Never,0,,,,,,,,,,Never,Never,Never,,Less than once per year,Never,,,,,,,Never,Less than once per year,Never,
12766918301,6/23/2021 9:47,6/23/2021 9:49,,,,,,,,,,,Medicine and clinical research,,,,,,,,,,,,,,,,Retired,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,>20,10-Jan,,,,,None,,,Data,,,,,,,,,,Biopsies,,,,,Post-mortem tissue,,Never,Never,0,,,,,,,,,,,,,,,,,,,,,,,,,
12765906501,6/23/2021 4:21,6/23/2021 4:28,,,,,,,,,Genetics and genomics,,,,,,,,,,,,,,,Government,,,,Male,,United States,,Research doctorate (e.g. PhD),,,>20,>100,,,,,None,,Samples,Data,,,,,,,,,2D cell culture,Biopsies,,,,,Post-mortem tissue,,Never,Never,5-Jan,Sometimes,In cancer research some level of animal data is sometimes required.,Yes,In 1 study I can think of we performed mouse xenograft experiments,Own lab(s) or lab(s) of coauthors,,A coauthor had this facility,No,Cannot remember a case with over 400 publications,Often,N/A,N/A,,Several times per month,Never,,,,,,,At least once per year,At least once per year,N/A,I rarely review papers with animal data
12764230321,6/22/2021 13:19,6/22/2021 13:45,,,,,,,,,,,,,,,,,,,,Toxicology,,Academia/Research institution,,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,>20,>100,Models,Samples,Data,Materials,,Models,Samples,Data,Materials,,,,,,,,,,Computational,Live organisms,,,,,Always,Never,0,,,,,,,,,,Never,Never,Never,"I have published results from animal studies, results of correlations between animals studies and human studies with the same chemicals. Also computerize methods for animal studies. Reviewer have asked questions, made suggestions etc. but never asked to add in vitro studies to animal or human studies.",At least once per year,Never,,,,,,,Never,Never,Less than once per year,The type of data I have requested is better or additional statistical analysis.  
12763989692,6/22/2021 11:39,6/22/2021 11:41,,,,,,,,,,,,,,,,,,,,,law student ,,,,Nonprofit/NGO,,,Female,,United States,,,,BSN,0-5,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12696491194,5/28/2021 3:17,6/22/2021 0:51,,,Biotechnology,,,,,,,,,,,,,,,,,,,,,Government,,,,Nonbinary,,Afghanistan,,,"Medical degree (e.g. MD, DDS)",,10-Jun,>100,Models,,,,,,,,,,,,,,,,,,,,,"Organoids, spheroids",,,Often,Often,20-Nov,Sometimes,,No,,,,,Sometimes,,Sometimes,Rarely,Always,,At least once per year,Several times per month,,,Preference for animal-based methods,,,,At least once per year,At least once per month,Several times per month,
12760489462,6/21/2021 9:04,6/21/2021 9:10,Anthropology,,,,Disease research,,,Evolutionary biology,Genetics and genomics,,Medicine and clinical research,,Molecular and cellular biology,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,20-Nov,>100,Models,,,,,Models,,,,,,,,,,,2D cell culture,Biopsies,Computational,Live organisms,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",Post-mortem tissue,,Sometimes,Sometimes,10-Jun,Sometimes,,Sometimes,,Combination,,,Yes,,Often,Often,Often,,Several times per month,Never,,,,,,,At least once per month,At least once per month,At least once per year,
12715649425,6/4/2021 6:15,6/4/2021 6:20,,,,,,,,,,,,,,,,Pharmacology,,,,,,Academia/Research institution,Industry,,,,,Male,,India,,Research doctorate (e.g. PhD),,,0-5,10-Jan,Models,Samples,Data,Materials,,,,,,None,,,,,None,,,,,Live organisms,,,Post-mortem tissue,,Always,Never,N/A; e.g. if you've only submitted studies with animal-based experiments,,,,,,,,,,Never,Rarely,Sometimes,NA,Several times per month,Several times per month,,,Preference for animal-based methods,,,Non animal models Don’t represent actual biology and kinetics,At least once per year,Less than once per year,Several times per week,I get data since rationale is there. Reproducibility and real time data is required for drugs.
12709727659,6/2/2021 9:06,6/2/2021 11:20,,,,,,,,,,,,,Molecular and cellular biology,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Male,,Brazil,,Research doctorate (e.g. PhD),,,>20,>100,Models,,,,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,Biopsies,,Live organisms,,"Organoids, spheroids",Post-mortem tissue,,Sometimes,Never,5-Jan,Sometimes,,Yes,,Additional collaborators,,,No,,Often,Rarely,Sometimes,,At least once per month,Less than once per year,,,,,Depends on the conclusions and hypothesis raised by the authors,,At least once per year,Less than once per year,At least once per year,
12706165966,6/1/2021 10:37,6/1/2021 10:55,,,,,,,,,,,,,Molecular and cellular biology,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Male,,Brazil,,Research doctorate (e.g. PhD),,,>20,>100,,,,,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,Biopsies,,,,"Organoids, spheroids",Post-mortem tissue,,Rarely,Rarely,5-Jan,,,,,,,,,,,,,,,,,,,,,,,,,
12705825323,6/1/2021 9:01,6/1/2021 9:07,,,,Computational biology,,,,Evolutionary biology,Genetics and genomics,,,,,,,,,,,,,Academia/Research institution,,,,,,Male,,Brazil,,Research doctorate (e.g. PhD),,,20-Nov,41-100,,,,,None,,,Data,,,,,,,,,,,Computational,,,,,,Never,Never,5-Jan,Sometimes,"In some circumstances the added information would indeed provide extra validation, but it was not essential.",No,My group is purely computational.,,,,Not sure,,Never,N/A,N/A,,At least once per month,Less than once per year,,,,Unaware of nonanimal or alternative methods for the given hypothesis,,,At least once per year,At least once per year,Less than once per year,
12704946627,6/1/2021 4:24,6/1/2021 4:29,,,,,,,,,,,,Microbiology,,,,,,,,,,Academia/Research institution,,,,,,Female,,Germany,,Research doctorate (e.g. PhD),,,0-5,10-Jan,,,,,,,,,,,,Samples,,,,Do you count in animal-based if I use human blood?,2D cell culture,,,Live organisms,,,,blood,Never,Never,5-Jan,No,,No,,,,,Not sure,,Often,N/A,N/A,,Less than once per year,Less than once per year,,,,Unaware of nonanimal or alternative methods for the given hypothesis,,,,,,
12703673641,5/31/2021 15:19,5/31/2021 15:27,,,,,,,,,,,,,,Neuroscience,,,,,,,,Academia/Research institution,,,,,,Female,,Brazil,,Research doctorate (e.g. PhD),,,20-Nov,10-Jan,,Samples,,,,,,,,,,,,,,,,,,Live organisms,,,,,Always,Rarely,0,,,,,,,,,,Never,Never,Always,,At least once per year,Never,,,,,,,Never,Less than once per year,Less than once per year,
12702518324,5/31/2021 4:32,5/31/2021 4:33,,,,,,,,,,,,Microbiology,,,,,,,,,,Academia/Research institution,,Government,,,,Female,,India,Master's degree,,,,0-5,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12702495130,5/31/2021 4:20,5/31/2021 4:31,,,,,Disease research,,,,,,,,Molecular and cellular biology,Neuroscience,,,,,,Toxicology,,,,Government,,,,Female,,Italy,,Research doctorate (e.g. PhD),,,20-Nov,41-100,,,Data,,,Models,Samples,,Materials,,,,,,,,2D cell culture,,,,,"Organoids, spheroids",,,Never,Never,5-Jan,No,"merely requested to confirm in vitro data, no added value",Sometimes,to satisfy reviewers' request flank (subcutaneous) injections on tumor cells were performed ,Own lab(s) or lab(s) of coauthors,,member of my lab had access to animal facility and experience with performing the in vivo procedure,No,"normally, when in vivo data were provided articles were accepted",Sometimes,N/A,N/A,,At least once per month,Never,,,,,,,At least once per year,At least once per month,Less than once per year,"sometimes additional experiments are needed to gather further mechanistic understanding of described results, and nonanimal experiments serve this purpose"
12702489458,5/31/2021 4:16,5/31/2021 4:22,,,,,,,,,Genetics and genomics,,,,,,,,,,,,,Academia/Research institution,,,,,,Female,,Pakistan,,Research doctorate (e.g. PhD),,,0-5,10-Jan,,,,,None,,Samples,Data,Materials,,,,,,None,,,,Computational,,,,,,Never,Never,0,,,,,,,,,,Never,Never,Never,,At least once per year,Never,,,,,,,Never,Never,Never,
12699866434,5/29/2021 14:03,5/29/2021 14:10,,,,,Disease research,,,,,,,,Molecular and cellular biology,,,,,,,,,Academia/Research institution,,,,,,Female,,Netherlands,,Research doctorate (e.g. PhD),,,0-5,21-40,,,,Materials,,Models,Samples,Data,,,,,,,,,2D cell culture,Biopsies,,Live organisms,,"Organoids, spheroids",,,Rarely,Never,10-Jun,No,The need for validation of human organoid data with animal studies... just because journal reviewers were used to this,No,"We wrote a rebuttal to the editor, no success. Submitted elsewhere (high impact) accepted within 2 months ",,,,No,Xx,Often,N/A,N/A,Xx,Several times per month,Never,,,,,,,Several times per month,Several times per month,Never,No
12698277088,5/28/2021 14:46,5/28/2021 14:49,,,,,,,,,,,,,,,,,,,,Toxicology,,,Industry,,,,,Female,,United States,,,"Medical degree (e.g. MD, DDS)",,10-Jun,10-Jan,Models,,,,,,,,,,,,,,,,,,,Live organisms,,,,,Always,Never,0,,,,,,,,,,Often,Often,Sometimes,,Never,,,,,,,,,,,
12697879704,5/28/2021 11:51,5/28/2021 11:56,,,Biotechnology,,Disease research,,,,,,Medicine and clinical research,,Molecular and cellular biology,,,Pharmacology,,,Systems biology,Toxicology,,Academia/Research institution,,,,,,Female,,Canada,,Research doctorate (e.g. PhD),,,20-Nov,20-Nov,,,,,None,Models,Samples,,,,,,,,,,2D cell culture,,Computational,,"Microphysiological systems, organ chips, tissue chips","Organoids, spheroids",Post-mortem tissue,,Never,Never,5-Jan,No,They wanted human in vitro data to be “validated” against an animal model.  ,No,Justified why I shouldn’t have to.,,,,No,,Often,Never,Often,No,At least once per year,Never,,,,,,,,,,
12696785250,5/28/2021 5:29,5/28/2021 5:37,,,,Computational biology,,,,,,,,,,,,Pharmacology,,,,Toxicology,,Academia/Research institution,,,,,,Female,,Italy,Master's degree,Research doctorate (e.g. PhD),,,10-Jun,41-100,,,Data,,,Models,Samples,Data,Materials,,,,,,,,2D cell culture,,Computational,,,,,,Never,Never,5-Jan,No,"We elucidated a MOA using only gene expression data from hepatocytes in vitro. We were asked to perform the same in vivo, to confirm the findings.",No,The paper was withdrawn and used only as chapter in my PhD thesis,,,,Not sure,,Rarely,Never,Never,,At least once per month,Never,,,,,,,Less than once per year,At least once per year,Never,
12696640273,5/28/2021 4:31,5/28/2021 4:35,,,,,,,,,,,,,,Neuroscience,,,,,,,,Academia/Research institution,,Government,,,,Female,,Germany,,Research doctorate (e.g. PhD),,,20-Nov,20-Nov,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
12696589692,5/28/2021 4:01,5/28/2021 4:19,,,,,,Ecology,,,,,,,,,,,,,,,,Academia/Research institution,,,,,,Female,,Faroe Islands,,Research doctorate (e.g. PhD),,,10-Jun,10-Jan,Models,Samples,Data,,,,,,,,,,,,,,,,,Live organisms,,,,,Always,Never,0,,,,,,,,,,N/A,Never,Never,,At least once per year,Never,,,,,,,Never,Never,Never,
12696574098,5/28/2021 4:06,5/28/2021 4:15,,Biochemistry and biophysics,Biotechnology,Computational biology,,,,,,,,,Molecular and cellular biology,,,,,,Systems biology,Toxicology,,Academia/Research institution,,,,,,Female,,Greece,,Research doctorate (e.g. PhD),,,0-5,20-Nov,Models,,,,,,,,,,,,,,,,,,,Live organisms,,,,,Sometimes,Rarely,5-Jan,No,,No,,,,,Not sure,,Never,Sometimes,Never,,Several times per month,Less than once per year,,,Preference for animal-based methods,Unaware of nonanimal or alternative methods for the given hypothesis,,,At least once per month,Several times per month,Less than once per year,
12694091478,5/27/2021 9:26,5/27/2021 9:32,,,,,,,,,,,,,,,,Pharmacology,,,,,,Academia/Research institution,,,,,,Male,,United States,,Research doctorate (e.g. PhD),,,>20,>100,Models,Samples,Data,,,Models,Samples,,,,,,,,,,2D cell culture,Biopsies,,Live organisms,,"Organoids, spheroids",,,Sometimes,Sometimes,5-Jan,Yes,,Yes,,Own lab(s) or lab(s) of coauthors,,,Yes,,Sometimes,Sometimes,Sometimes,,Several times per week,At least once per month,,,,Unaware of nonanimal or alternative methods for the given hypothesis,,,Several times per month,At least once per month,At least once per month,