[Influence of the preservative thiomersal on the Interleukin-1-Beta release of human peripheral blood cells] [Article in German] LINZ 2000

Main Article Content

Matthias Fischer
Brigitte Keller-Stanislawski
Susanne Schober-Bendixen
Rudolf Schosser
Katrin Hacke
Thomas Hartung
Thomas Montag

Abstract

Several vaccines have been tested in the human whole blood pyrogen test as an alternative to the rabbit pyrogen test. As reported previously by our group, the alternative testsystem is basically applicable to vaccines. The widely used conservative thiomersal is influencing the test system. Surprisingly, the induction of fever inducing cytokines by endotoxin contaminations and other pyrogens can be suppressed by thiomersal.

Article Details

How to Cite
Fischer, M., Keller-Stanislawski, B., Schober-Bendixen, S., Schosser, R., Hacke, K., Hartung, T. and Montag, T. (2001) “[Influence of the preservative thiomersal on the Interleukin-1-Beta release of human peripheral blood cells] [Article in German]: LINZ 2000”, ALTEX - Alternatives to animal experimentation, 18(1), pp. 47-49. Available at: https://www.altex.org/index.php/altex/article/view/1374 (Accessed: 26October2021).
Section
Articles

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>