[An in vitro test system for evaluation of human-immunotoxicological actions of polychlorinated biphenyls (PCB)] [Article in German]

Article Sidebar

pdf
Published: May 1, 1999

Main Article Content

Winfried Ahne
Tierärztliche Fakultät der Ludwig Maximilians Universität D-München

Abstract

An in vitro test system using isolated human leukocytes for evaluation of immunotoxicological actions of polychlorinated biphenyls (PCB) is described. Immunotoxic effects of PCB 77, PCB 126 could be demonstrated by evaluation of the production of interleukin IL-1alpha, IL-2 and the tumor necrosis factor (TNF-alpha) of stimulated human leukocytes. The release of IL-1alpha, IL-2 and TNF-alpha was suppressed up to 60-80% by 0,05 ng of the PCB.

Article Details

How to Cite
Ahne, W. (1999) “[An in vitro test system for evaluation of human-immunotoxicological actions of polychlorinated biphenyls (PCB)] [Article in German]”, ALTEX - Alternatives to animal experimentation, 16(2), pp. 84–86. Available at: https://www.altex.org/index.php/altex/article/view/1464 (Accessed: 4 October 2023).
Issue
Vol. 16 No. 2 (1999)
Section
Short Communications
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Articles are distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is appropriately cited (CC-BY). Copyright on any article in ALTEX is retained by the author(s).