[An in vitro test system for evaluation of human-immunotoxicological actions of polychlorinated biphenyls (PCB)] [Article in German]

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Published: May 1, 1999

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Winfried Ahne
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Abstract

An in vitro test system using isolated human leukocytes for evaluation of immunotoxicological actions of polychlorinated biphenyls (PCB) is described. Immunotoxic effects of PCB 77, PCB 126 could be demonstrated by evaluation of the production of interleukin IL-1alpha, IL-2 and the tumor necrosis factor (TNF-alpha) of stimulated human leukocytes. The release of IL-1alpha, IL-2 and TNF-alpha was suppressed up to 60-80% by 0,05 ng of the PCB.

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How to Cite
Ahne, W. (1999) “[An in vitro test system for evaluation of human-immunotoxicological actions of polychlorinated biphenyls (PCB)] [Article in German]”, ALTEX - Alternatives to animal experimentation, 16(2), pp. 84–86. Available at: https://www.altex.org/index.php/altex/article/view/1464 (Accessed: 20 April 2024).
Issue
Vol. 16 No. 2 (1999)
Section
Short Communications
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