[Different concepts for risk assessment have to be applied if the data are derived from testing in animals or from testing in vitro] [Article in German]
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Abstract
In vitro tests are well accepted by toxicologist for mechanistic studies but they have so far not been able to replace testing in animals for regulatory purposes, as e.g. risk assessment and risk management. This is basically due to differences in the quality of results obtained from in vivo and in vitro studies. Therefore, a new concept for risk assessment and risk management is proposed which is entirely based upon data from in vitro tests.
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