[The sophisticated process of validation] [Article in German]

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Thomas Hartung, Horst Spielmann
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Current concepts on the efficient performance of validation studies are summarised. From the experience of recent attempts to validate alternative methods to animal experiments, the difficult procedure of validation should be refined. The applications of toxicological tests (safety testing) and pharmacological methods (identification of putative drugs) require different validation strategies. Suggestions as to an improved design of test development, evaluation, pre-validation, definitive validation as well as final assessment of the result are presented.

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Hartung, T. and Spielmann, H. (1995) “[The sophisticated process of validation] [Article in German]”, ALTEX - Alternatives to animal experimentation, 12(2), pp. 98–103. Available at: https://www.altex.org/index.php/altex/article/view/1677 (Accessed: 20 July 2024).
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