[Production of monoclonal antibodies in chicken eggs] [Article in German]

Andreas Hlinak; Uwe Marx; Volker Jäger

pdf

Published: May 1, 1994

Keywords:

monoclonal antibody, hybridoma technique, chicken egg, alternative antibody production

Andreas Hlinak, Uwe Marx, Volker Jäger
[show affiliations]

Abstract

The possibility to produce monoclonal antibodies in chicken eggs was shown. Knowledge of biochemical and biophysical parameters of eggs were the basic of the experiments. The cell clones produced 0.1 mg/ml of antibodies in the egg fluid. This method can be an alternative to the monoclonal antibody production in mouse ascites or in bioreactors.

How to Cite

Hlinak, A., Marx, U. and Jäger, V. (1994) “[Production of monoclonal antibodies in chicken eggs] [Article in German]”, ALTEX - Alternatives to animal experimentation, 11(2), pp. 85–91. Available at: https://www.altex.org/index.php/altex/article/view/1707 (Accessed: 28 March 2025).

Issue

Vol. 11 No. 2 (1994)

Section

Articles

Articles are distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is appropriately cited (CC-BY). Copyright on any article in ALTEX is retained by the author(s).

Most read articles by the same author(s)

Uwe Marx, Tommy B. Andersson, Anthony Bahinski, Mario Beilmann, Sonja Beken, Flemming R. Cassee, Murat Cirit, Mardas Daneshian, Susan Fitzpatrick, Olivier Frey, Claudia Gaertner, Christoph Giese, Linda Griffith, Thomas Hartung, Minne B. Heringa, Julia Hoeng, Wim H. de Jong, Hajime Kojima, Jochen Kuehnl, Marcel Leist, Andreas Luch, Ilka Maschmeyer, Dmitry Sakharov, Adrienne J. A. M. Sips, Thomas Steger-Hartmann, Danilo A. Tagle, Alexander Tonevitsky, Tewes Tralau, Sergej Tsyb, Anja van de Stolpe, Rob Vandebriel, Paul Vulto, Jufeng Wang, Joachim Wiest, Marleen Rodenburg, Adrian Roth, Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing , ALTEX - Alternatives to animal experimentation: Vol. 33 No. 3 (2016)
Sarah Gordon, Mardas Daneshian, Joke Bouwstra, Francesca Caloni, Samuel Constant, Donna E. Davies, Gudrun Dandekar, Carlos A. Guzman, Eric Fabian, Eleonore Haltner, Thomas Hartung, Nina Hasiwa, Patrick Hayden, Helena Kandarova, Sangeeta Khare, Harald F. Krug, Carsten Kneuer, Marcel Leist, Guoping Lian, Uwe Marx, Marco Metzger, Katharina Ott, Pilar Prieto, Michael S. Roberts, Erwin Roggen, Tewes Tralau, Claudia van den Braak, Heike Walles, Claus-Michael Lehr, Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology , ALTEX - Alternatives to animal experimentation: Vol. 32 No. 4 (2015)
Mario Beilmann, Harrie Boonen, Andreas Czich, Gordon Dear, Philip Hewitt, Tomas Mow, Peter Newham, Teija Oinonen, Francois Pognan, Adrian Roth, Jean-Pierre Valentin, Freddy Van Goethem, Richard Weaver, Barbara Birk, Scott Boyer, Francesca Caloni, Alice Chen, Raffaella Corvi, Mark Cronin, Mardas Daneshian, Lorna Ewart, Rex Fitzgerald, Geraldine Hamilton, Thomas Hartung, Joshua Kangas, Nynke Kramer, Marcel Leist, Uwe Marx, Sebastian Polak, Costanza Rovida, Emanuela Testai, Bob van der Water, Paul Vulto, Thomas Steger-Hartmann, Optimizing drug discovery by investigative toxicology: Current and future trends , ALTEX - Alternatives to animal experimentation: Vol. 36 No. 2 (2019)
Uwe Marx, Takafumi Akabane, Tommy B. Andersson, Elizabeth Baker, Mario Beilmann, Sonja Beken, Susanne Brendler-Schwaab, Murat Cirit, Rhiannon David, Eva-Maria Dehne, Isabell Durieux, Lorna Ewart, Suzanne C. Fitzpatrick, Olivier Frey, Florian Fuchs, Linda G. Griffith, Geraldine A. Hamilton, Thomas Hartung, Julia Hoeng, Helena Hogberg, David J. Hughes, Donald E. Ingber, Anita Iskandar, Toshiyuki Kanamori, Hajime Kojima, Jochen Kuehnl, Marcel Leist, Bo Li, Peter Loskill, Donna L. Mendrick, Thomas Neumann, Giorgia Pallocca, Ivan Rusyn, Lena Smirnova, Thomas Steger-Hartmann, Danilo A. Tagle, Alexander Tonevitsky, Sergej Tsyb, Martin Trapecar, Bob van de Water, Janny van den Eijnden-van Raaij, Paul Vulto, Kengo Watanabe, Armin Wolf, Xiaobing Zhou, Adrian Roth, Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development , ALTEX - Alternatives to animal experimentation: Vol. 37 No. 3 (2020)
Matthias Fischer, Andreas Hlinak, An ELISA for the quantification of chicken immunoglobulin (IgY) in various liquid media , ALTEX - Alternatives to animal experimentation: Vol. 13 No. 4 (1996)
Rüdiger Schade, Wolf Bürger, Torsten Schöneberg, Anne Schniering, Christine Schwarzkopf, Andreas Hlinak, Hartmut Kobilke, [Avian egg yolk antibodies] [Article in German] , ALTEX - Alternatives to animal experimentation: Vol. 11 No. 2 (1994)
Rüdiger Schade, Anne Schniering, Andreas Hlinak, [Polyclonal avian antibodies extracted from egg yolk as an alternative to the production of antibodies in mammals - a review] [Article in German] , ALTEX - Alternatives to animal experimentation: Vol. 9 No. 2 (1992)
Rüdiger Schade, Andreas Hlinak, Egg yolk antibodies, state of the art and future prospects , ALTEX - Alternatives to animal experimentation: Vol. 13 No. Supp. 1 (1996): Egg yolk antibodies, IgY technology
Andreas Hlinak, Monika Krüger, Thomas Bartels, Mirko Sasse, Marina Claros, Rüdiger Schade, Studies on diagnostic applications of egg yolk antibodies against Bordetella bronchiseptica , ALTEX - Alternatives to animal experimentation: Vol. 13 No. Supp. 1 (1996): Egg yolk antibodies, IgY technology
Andreas Hlinak, Wieland Schrödl, Sabine Witt, Rüdiger Schade, Monika Krüger, Production of egg yolk antibodies against human cell-associated antigens , ALTEX - Alternatives to animal experimentation: Vol. 13 No. Supp. 1 (1996): Egg yolk antibodies, IgY technology

1 2 > >>

Article Sidebar

Main Article Content

Abstract

Article Details

Most read articles by the same author(s)