20 Years 3R Research Foundation Switzerland

Main Article Content

Franz P. Gruber

Abstract

Editorial
Peter Maier and Hugo Wick

Contents

COMPLETED PROJECTS


Pierre Aeby, François Python and Carsten Goebel
Skin sensitisation: Understanding the in vivo situation for the development of reliable in vitro test approaches


Margarete Arras
Improvement of pain therapy in laboratory mice


Yara Banz and Robert Rieben
Exploring natural anticoagulation by endothelial cells: A novel in vitro model


Nicolau Beckmann
Non-invasive methods: Investigation of airways diseases by MRI in rats


Gerd Bicker, Andrea Gierse, Saime Tan and François Paquet-Durand
Simulation of stroke-related damage in cultured human nerve cells


Frank O. Bootz and Felix R. Wolf
Animal-free screening of biological materials for contamination by rodent viruses


Arie Bruinink and Peter Maier
Identification of neurotoxic chemicals in cell cultures


Karl Fent
Permanent fish cell cultures as important tools in ecotoxicology


Andrew Hemphill
Generation of parasite cysts in cultured cells instead of living animals


Paul Honegger and Beatriz Pardo
 
Aggregating brain cell cultures: Investigation of stroke related brain damage


Rok Humar, Lourdes Sanchez de Miguel, Fabrice N. Kiefer, Edouard J. Battegay: Formation of new blood vessels in the heart can be studied in cell cultures


Thomas Kröber and Patrick Guerin
The tick blood meal: From a living animal or from a silicone membrane?


Regine Landmann-Suter
Generation and use of a mouse Kupffer cell line


Claudia Mertens and Thomas Rülicke
Welfare assessment and phenotype characterisation of transgenic mice


Werner J. Pichler
Predicting drug hypersensitivity by in vitro tests


Valeska Reichel, Carsten Baehr and Gert Fricker
From blood to brain and vice versa: Transport processes in choroid plexus can be studied in vitro


Geoff Richards, Martin J. Stoddart, Angharad E. Simpson and Pamela I. Furlong Establishing a 3D ex vivo culture system for investigations of bone metabolism and biomaterial interactions


Stefanie Schindler, Stefan Fennrich, Reto Crameri, Thomas W. Jungi, Thomas Montag, Thomas Hartung
Fever in the test tube – towards a human(e) pyrogen test


Angelo Vedani, Markus A. Lill and Max Dobler
Predicting the toxic potential of drugs and chemicals in silico


Eva Waiblinger and Barbara König
Housing and husbandry conditions affect stereotypic behaviour in laboratory gerbils 67


Hanno Würbel
Environmental enrichment does not disrupt standardization of animal experiments


 


PROJECTS IN PROGRESS


Anna Bogdanova and Johannes Vogel
Isolated, autologous blood-perfused heart: Replacement of heterotopic heart transplantation


Paolo Cinelli
Assessment of pain and stress in mice by monitoring gene expression changes


Pierre Cosson
A non-mammalian system to study bacterial infections


Beate Escher
Development of QSAR-models for classification and prediction of baseline toxicity and of uncoupling of energy transduction


Beate Escher and Jung-Hwan Kwon
Development of an in vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish system


Paul Flecknell, Jon Gledhill and Claire Richardson
Assessing animal health and welfare and recognising pain and distress


Marianne Geiser and Doris Lang
In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction


Norbert Goebels
Organotypic CNS slice cultures as an in vitro model for immune mediated tissue damage and repair in multiple sclerosis


Regina Hofmann-Lehmann and Ludwig Hoelzle
Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas


Cynthia Lee and Mauro Alini
The development of an in vitro intervertebral disc organ culture


Stephen L. Leib
An in vitro model of central nervous system infection and regeneration: Neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis


Alexander Mathis
Development of a three-dimensional enteric cell culture model for In vitro studies of the intestinal eukaryotic parasites Cryptosporidium spp.


Christoph Mueller
Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets


Omolara Ogunshola
Development of a novel multicellular 3-dimensional blood brain barrier in vitro model


Elisabetta Padovan
Adjuvanticity of microbial-derived particles and synthetic analogs in vitro


Nicolas Ruggli and Artur Summerfield
Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates


Claudio Strebel
Information on serum free cell lines, an interactive database


Imprint

Article Details

How to Cite
Gruber, F. P. (2007) “20 Years 3R Research Foundation Switzerland”, ALTEX - Alternatives to animal experimentation, 24(Supp), pp. 1-104. Available at: https://www.altex.org/index.php/altex/article/view/2210 (Accessed: 18April2021).
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