Editorial

Editorial

Walter Pfaller

1

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Editorial

Horst Spielmann

2-3

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Articles

[Science and Ethics] [Article in German]

Friedrich Harrer

5-9

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[Experimental animal research in the EU legislation] [Article in German]

Gieri Bolliger

10-19

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[White Paper of the European Commission - strategy for a new chemicals policy] [Article in German]

Horst Spielmann

20-25

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The new EU Chemicals Policy - Discussions on details relevant for animal welfare

Ursula G. Sauer

26-29

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Ecotoxicological assessment of surface waters: A modular approach integrating in vitro methods

Nina Schweigert, Rik I. L. Eggen, Beate I. Escher, Patricia Burkhardt-Holm, Renata Behra

30-37

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DarT: The embryo test with the zebrafish Danio rerio - a general model in ecotoxicology and toxicology

Roland Nagel

38-48

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[PCR and ELISA - in vitro alternatives to the mouse-bioassay for assessing the Botulinum-Neurotoxin-C1 production potential in environmental samples?] [Article in German]

Thomas Zechmeister, Andreas H. Farnleitner, Tonie E. Rocke, Fritz Pittner, Renate Rosengarten, Robert L. Mach, Alois Herzig, Alexander K. T. Kirschner

49-54

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[Improving the embryonic stem cell test (EST) by establishing molecular endpoints of tissue specific development using murine embryonic stem cells (D3 cells)] [Article in German]

Andrea Seiler, Anke Visan, Ingeborg Pohl, Elke Genschow, Roland Buesen, Horst Spielmann

55-63

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Immortalisation of ovarian granulosa and theca cells of the marmoset monkey Callithrix jacchus

Bettina Husen, Kai Lieder, Alexandra Marten, Angelika Jurdzinski, Kerstin Fuhrmann, Harald Petry, Wolfgang Lüke, Almuth Einspanier

64-72

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Comparative study of rabbit pyrogen test and human whole blood assay on human serum albumin

Ingo Spreitzer, Matthias Fischer, Katja Hartzsch, Ursel Lüderitz-Püchel, Thomas Montag

73-75

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[Replacement of Mouse and Rat Antibody Production Test. Validation of Different Polymerase Chain Reaction Assays] [Article in German]

Frank Bootz, Isabella Sieber

76-86

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Standardised in vitro Electrophysiologic Measurements Using Isolated Perfused Porcine Hearts - Assessment of QT Interval Alterations

Inga Ast, Dagmar Heydeck, Eckhard Mothes, Bruno Christ

87

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Editorial material

Letter, Program

Franz P. Gruber

88

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Imprint

Imprint

Franz P. Gruber

U3

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Cover

Cover

Franz P. Gruber

U1-U4

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