Editorial

Sonja von Aulock

Green toxicology

Alexandra Maertens, Nicholas Anastas, Pamela J. Spencer, Martin Stephens, Alan Goldberg, Thomas Hartung

Consensus report on the future of animal-free systemic toxicity testing

Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet, Anna-Maria Rossi, Michael Schwarz, Martin Stephens, Rob Taalman, Thomas B. Knudsen, James McKim, Georgina Harris, David Pamies, Thomas Hartung

International ring trial of the epidermal equivalent sensitizer potency assay: reproducibility and predictive capacity

Marc A. T. Teunis, Sander W. Spiekstra, Mieke Smits, Els Adriaens, Tobias Eltze, Valentina Galbiati, Cyrille Krul, Robert Landsiedel, Raymond Pieters, Judith Reinders, Erwin Roggen, Emanuela Corsini, Susan Gibbs

Controversial role of gamma-glutamyl transferase activity in cisplatin nephrotoxicity

Lukas Fliedl, Matthias Wieser, Gabriele Manhart, Matthias P. Gerstl, Abdulhameed Khan, Johannes Grillari, Regina Grillari-Voglauer

Developmental toxicity of thyroid-active compounds in a zebrafish embryotoxicity test

Barae Jomaa, Sanne A. B. Hermsen, Maurijn Y. Kessels, Johannes H. J. van den Berg, Ad A. C. M. Peijnenburg, Jac M. M. J. G. Aarts, Aldert H. Piersma, Ivonne M. C. M. Rietjens

Open source software implementation of an integrated testing strategy for skin sensitization potency based on a Bayesian network

Jason R. Pirone, Marjolein Smith, Nicole C. Kleinstreuer, Thomas A. Burns, Judy Strickland, Yuri Dancik, Richard Morris, Lori A. Rinckel, Warren Casey, Joanna S. Jaworska

State of the art on alternative methods to animal testing from an industrial point of view: Ready for regulation?

Rachel Ashton, Bart De Wever, Horst W. Fuchs, Marianna Gaca, Erin Hill, Cyrille Krul, Albrecht Poth, Erwin L. Roggen

Developing microphysiological systems for use as regulatory tools – challenges and opportunities

Melvin E. Andersen, Kellyn Betts, Yvonne Dragan, Suzanne Fitzpatrick, Jesse L. Goodman, Thomas Hartung, Jonathan Himmelfarb, Donald E. Ingber, Abigail Jacobs, Robert Kavlock, Kyle Kolaja, James L. Stevens, Dan Tagle, D. Lansing Taylor, Douglas Throckmorton

3Rs and new frontiers in laboratory techniques

Francesca Caloni, Gianni Dal Negro, Patrizia Costa, Silvia Dotti, Giacomo Matteucci, Augusto Vitale, Isabella De Angelis

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