Editorial

Sonja von Aulock

249

Regulatory acceptance and use of 3R models: a multilevel perspective

Marie-Jeanne W. A. Schiffelers, Bas J. Blaauboer, Coenraad F. M. Hendriksen, Wieger E. Bakker

287-300

Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model

Fransisca Leonard, Hussain Ali, Eva-Maria Collnot, Bart J. Crielaard, Twan Lammers, Gert Storm, Claus-Michael Lehr

275-285

Characterization of mouse cell line IMA 2.1 as a potential model system to study astrocyte functions

Stefan Schildknecht, Susanne Kirner, Anja Henn, Karlo Gasparic, Regina Pape, Liudmila Efremova, Olaf Maier, Roman Fischer, Marcel Leist

261-274

Reproductive and developmental toxicity testing: from in vivo to in vitro

Elizabeth Stallman Brown, Abigail Jacobs, Suzanne Fitzpatrick

333-339

Corners

Sonja von Aulock

340-348

News

Sonja von Aulock

349-355

Calendar

Sonja von Aulock

301

Imprint

Sonja von Aulock

356

Instructions to authors

Sonja von Aulock

286

Cover

Sonja von Aulock