Editorial

Franz P. Gruber

Animal testing and its alternatives – the most important omics is economics

Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

Anna Bal-Price, Helena T. Hogberg, Kevin M. Crofton, Mardas Daneshian, Rex E. FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H. Piersma, Magdalini Sachana, Timothy J. Shafer, Andrea Terron, Florianne Monnet-Tschudi, Barbara Viviani, Tanja Waldmann, Remco H. S. Westerink, Martin F. Wilks, Hilda Witters, Marie-Gabrielle Zurich, Marcel Leist

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

David Pamies, Anna Bal-Price, Christophe Chesné, Sandra Coecke, Andras Dinnyes, Chantra Eskes, Regina Grillari, Gerhard Gstraunthaler, Thomas Hartung, Paul Jennings, Marcel Leist, Ulrich Martin, Robert Passier, Jens C. Schwamborn, Glyn N. Stacey, Heidrun Ellinger-Ziegelbauer, Mardas Daneshian

Investigation of ruminant xenobiotic metabolism in a modified rumen simulation system (RUSITEC)

Barbara Birk, Alexander Staehle, Mathias Meier, Markus Palm, Dorothee Funk-Weyer, Gerhard Breves, Harald Seulberger

A standardized method based on pigmented epidermal models evaluates sensitivity against UV-irradiation

Freia F. Schmid, Florian Groeber-Becker, Stefanie Schwab, Sibylle Thude, Matthias Goebeler, Heike Walles, Jan Hansmann

In vitro and in silico liver models: Current trends, challenges and opportunities

Andrey Poloznikov, Irina Gazaryan, Maxim Shkurnikov, Sergey Nikulin, Oxana Drapkina, Ancha Baranova, Alexander Tonevitsky

Regulatory acceptance of read-across

Megan Chesnut, Takashi Yamada, Timothy Adams, Derek Knight, Nicole Kleinstreuer, George Kass, Thomas Luechtefeld, Thomas Hartung, Alexandra Maertens

From 3Rs to 3D: In vitro alternative models for replacement

Andras-Laszlo Nagy, Cornel Catoi, Carmen Socaciu, Adela Pintea, Nechita A. Oros, Cristina Coman, Dumitrita Rugina, Cristian T. Matea, Teodora Mocan, Teresa Coccini, Uliana De Simone, Isabella De Angelis, Alessia Bertero, Yula Sambuy, Francesca Caloni

Corners

Sonja von Aulock

Imprint

Sonja von Aulock

Cover

Sonja von Aulock