Editorial

Sonja von Aulock

U2

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Food for Thought ...

Computational approaches to chemical hazard assessment

Thomas Luechtefeld, Thomas Hartung

459-478

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Articles

From in vivo to in vitro: The medical device testing paradigm shift

Dayna Kerecman Myers, Alan M. Goldberg, Albrecht Poth, Michael F. Wolf, Joseph Carraway, James McKim, Kelly P. Coleman, Richard Hutchinson, Ronald Brown, Harald F. Krug, Anthony Bahinski, Thomas Hartung

479-500

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Non-animal approaches for toxicokinetics in risk evaluations of food chemicals

Ans Punt, Ad A. C. M. Peijnenburg, Ron L. A. P. Hoogenboom, Hans Bouwmeester

501-514

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Evaluation of the GARD assay in a blind Cosmetics Europe study

Henrik Johansson, Robin Gradin, Andy Forreryd, Maria Agemark, Kathrin Zeller, Angelica Johansson, Olivia Larne, Erwin van Vliet, Carl Borrebaeck, Malin Lindstedt

515-523

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The borderline range of toxicological methods: Quantification and implications for evaluating precision

Maria Leontaridou, Daniel Urbisch, Susanne N. Kolle, Katharina Ott, Denis S. Mulliner, Silke Gabbert, Robert Landsiedel

525-538

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The GARD platform for potency assessment of skin sensitizing chemicals

Kathrin S. Zeller, Andy Forreryd, Tim Lindberg, Robin Gradin, Aakash Chawade, Malin Lindstedt

539-559

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Short communications

Adaptation of the KeratinoSens™ skin sensitization test to animal-product-free cell culture

Nathalie Belot, Bushra Sim, Christopher Longmore, Lottie Roscoe, Carol Treasure

560-564

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Letters

Progress towards the replacement of the rabbit blood sugar bioidentity assay by an in vitro test for batch release of insulins in quality control

Rüdiger Hack, Sabrina Rueggeberg, Lea Schneider, Dirk Mayert, Norbert Tennagels, Stefan Welte, Birgit Niederhaus, Wilfried Arz, Dirk Usener, Götz Troschau, Johannes Meiwes, Jochen Maas

565-566

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Corners

567-576

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News

577-580

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Calendar

524

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Imprint

U3

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Cover

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