ALTEX - Alternatives to animal experimentation

Latest Articles

Human platelet lysate as validated replacement for animal serum to assess chemosensitivity
Miriam Pons, Georg Nagel, Yanira Zeyn et al.
Prenatal developmental toxicity testing of petroleum substances using the zebrafish embryotoxicity test
Lenny Kamelia, Sylvia Brugman, Laura de Haan et al.
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches
Melissa Van Bossuyt, Els Van Hoeck, Tamara Vanhaecke et al.

News

January webinar on non-animal approaches for inhalation toxicity testing
2018-12-13
NICEATM Integrated Chemical Environment updated
2018-12-13

Current Issue Vol 35 No 4 (2018)

Published: October 24, 2018

Editorial

Sonja von Aulock

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Sex and media: Considerations for cell culture studies

Roberta de Souza Santos, Aaron P. Frank, Biff F. Palmer, Deborah J. Clegg

435-440

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A human population-based organotypic in vitro model for cardiotoxicity screening

Fabian Grimm, Alexander Blanchette, John S. House, Kyle Ferguson, Nan-Hung Hsieh, Chimeddulam Dalaijamts, Alec A. Wright, Blake Anson, Fred A. Wright, Weihsueh A. Chiu, Ivan Rusyn

441-452

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Material-mediated pyrogens in medical devices: Applicability of the in vitro Monocyte Activation Test

Lindsey K. Borton, Kelly P. Coleman

453-463

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Completely defined co-culture of adipogenic differentiated ASCs and microvascular endothelial cells

Ann-Cathrin Volz, Larissa Hack, Franziska B. Atzinger, Petra J. Kluger

464-476

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Adaptation of the human Cell Line Activation Test (h-CLAT) to animal-product-free conditions

Alexander Edwards, Lottie Roscoe, Christopher Longmore, Fiona Bailey, Bushra Sim, Carol Treasure

477-488

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Replacement of foot-and-mouth disease virus cattle tongue titration by in vitro titration

Aldo Dekker, Froukje van Hemert-Kluitenberg, Anna H. Oosterbaan, Kimberly Moonen, Laure Mouton

489-494

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Testing vaginal irritation with the Hen’s Egg Test-Chorioallantoic Membrane assay

Rita Palmeira-de-Oliveira, Rita Monteiro Machado, José Martinez-de-Oliveira, Ana Palmeira-de-Oliveira

495-503

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Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system

Brian D. Chapron, Alenka Chapron, Brian Phillips, Miracle C. Okoli, Danny D. Shen, Edward J. Kelly, Jonathan Himmelfarb, Kenneth E. Thummel

504-515

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Lowering the p-value from 0.05 to 0.005 conflicts with the 3R rules – an advocacy for alternatives to hypothesis testing with the p-value approach

Konradin Metze, Fernanda Aparecida Borges da Silva, Irene Lorand-Metze

516-517

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The ethical evaluation of animal experiments deserves more than empty phrases

Tilo Weber

518-519

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3Replacement Winter School – Out of the barriers: In vitro models in toxicology

Francesca Caloni, Yula Sambuy, Guerino Lombardi, Silvia Dotti, Isabella De Angelis

520-521

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Corners

522-526

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ALTEX Edition membership application

527

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Imprint

528

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TIERethik

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Cover

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View All Issues

Editorial

Food for Thought ...

Sex and media: Considerations for cell culture studies

Articles

A human population-based organotypic in vitro model for cardiotoxicity screening

Material-mediated pyrogens in medical devices: Applicability of the in vitro Monocyte Activation Test

Completely defined co-culture of adipogenic differentiated ASCs and microvascular endothelial cells

Adaptation of the human Cell Line Activation Test (h-CLAT) to animal-product-free conditions

Replacement of foot-and-mouth disease virus cattle tongue titration by in vitro titration

Testing vaginal irritation with the Hen’s Egg Test-Chorioallantoic Membrane assay

Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system

Letters

Lowering the p-value from 0.05 to 0.005 conflicts with the 3R rules – an advocacy for alternatives to hypothesis testing with the p-value approach

The ethical evaluation of animal experiments deserves more than empty phrases

Meeting Reports

3Replacement Winter School – Out of the barriers: In vitro models in toxicology

Corners

Editorial material

ALTEX Edition membership application

Imprint

TIERethik

Cover