ALTEX - Alternatives to animal experimentation

Latest Articles

Optimizing drug discovery by Investigative Toxicology: Current and future trends
Mario Beilmann, Harrie Boonen, Andreas Czich et al.
Workflow for Defining Reference Chemicals for Assessing Performance of In Vitro Assays
Richard S. Judson, Russell S. Thomas, Nancy Baker et al.
Human platelet lysate as validated replacement for animal serum to assess chemosensitivity
Miriam Pons, Georg Nagel, Yanira Zeyn et al.

News

Collaborative Acute Toxicity Modeling Suite (CATMoS) now available
2018-12-20
January webinar on non-animal approaches for inhalation toxicity testing
2018-12-13

Current Issue Vol 36 No 1 (2019)

Published: January 8, 2019

Editorial

Sonja von Aulock

U2

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Toward Good In Vitro Reporting Standards

Thomas Hartung, Rob de Vries, Sebastian Hoffmann, Helena T. Hogberg, Lena Smirnova, Katya Tsaioun, Paul Whaley, Marcel Leist

3-17

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A three-dimensional model to study human synovial pathology

Mathijs G. A. Broeren, Claire E. J. Waterborg, Renske Wiegertjes, Rogier M. Thurlings, Marije I. Koenders, Peter L. E. M. van Lent, Peter M. van der Kraan, Fons A. J. van de Loo

18-28

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An ex vivo porcine spleen perfusion as a model of bacterial sepsis

Wen Y. Chung, Joseph J. Wanford, Rohan Kumar, John D. Isherwood, Richard D. Haigh, Marco R. Oggioni, Ashley R. Dennison, Giuseppe Ercoli

29-38

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Investigating cell type specific mechanisms contributing to acute oral toxicity

Pilar Prieto, Rabea Graepel, Kirsten Gerloff, Lara Lamon, Magdalini Sachana, Francesca Pistollato, Laura Gribaldo, Anna Bal-Price, Andrew Worth

39-64

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Retrospective review of anesthetic and analgesic regimens used in animal research proposals

Kathrin Herrmann, Paul Flecknell

65-80

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Botulinum toxin testing on animals is still a Europe-wide issue

Katy Taylor, Corina Gericke, Laura Rego Alvarez

81-90

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Chemical hazard prediction and hypothesis testing using quantitative adverse outcome pathways

Edward J. Perkins, Kalyan Gayen, Jason E. Shoemaker, Philipp Antczak, Lyle Burgoon, Francesco Falciani, Steve Gutsell, Geoff Hodges, Aude Kienzler, Dries Knapen, Mary McBride, Catherine Willett, Francis J. Doyle III, Natàlia Garcia-Reyero

91-102

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Characterizing sources of variability in zebrafish embryo screening protocols

Jon T. Hamm, Patricia Ceger, David Allen, Matt Stout, Elizabeth A. Maull, Greg Baker, Amy Zmarowski, Stephanie Padilla, Edward Perkins, Antonio Planchart, Donald Stedman, Tamara Tal, Robert L. Tanguay, David C. Volz, Mitch S. Wilbanks, Nigel J. Walker

103-120

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Preclinical alternative model for analysis of porous scaffold biocompatibility in bone tissue engineering

Eva Petrovova, Maria Giretova, Alena Kvasilova, Oldrich Benada, Jan Danko, Lubomir Medvecky, David Sedmera

121-130

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Zebrafish embryo and acute fish toxicity test show similar sensitivity for narcotic compounds

Anita Birke, Stefan Scholz

131-135

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The current status of alternative methods for cosmetics safety assessment in China

Fei-ya Luo, Zhe Su, Jing Wu, Feng-lan Zhang, Shu-xia Xing, Gang-li Wang, Yong Lu

136-139

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Science instead of animal experiments

Corina Gericke, Silke Strittmatter

140-141

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Alternative methods to replace or reduce animal models in biomedical research

Florenza Lüder Ripoli, Manuela Buettner, André Bleich

141-142

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Is there an end in sight for animal testing?
Can organ-on-a-chip replace animal use in safety testing with advanced human-focused approaches?

Sonja von Aulock

142-144

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Advanced in vitro models analysis

Katarzyna S. Kopanska, Markus Rimann, Sandra Latenser, Michael Raghunath

144-147

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Corners

148-153

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Chemical concentrations in cell culture compartments (C5) – concentration definitions

Jaffar Kisitu, Susanne Hougaard Bennekou, Marcel Leist

154-160

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Imprint

U3

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EUSAAT 2019

U4

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