The Utrecht Advanced In Vitro Models (U-AIM) was officially launched on May 16, 2018. The goal of U-AIM is to become a “one-stop shop” where high potential in vitro models are being developed, validated and transitioned to stakeholders. Through a strong cooperation between scientists, students, regulators and industry, U-AIM aims to strongly reduce animal experimentation and increase market potential of innovative models. The 3Rs-Centre ULS is directly involved in the U-AIM activities.
The NC3Rs Gateway is a new publication portal on the F1000Research publication platform dedicated to the 3Rs, featuring methodology articles, reviews and source data that describe in detail how the use of animals in research can be replaced, reduced or refined. All articles will be published almost immediately and then undergo invited open peer review.
In a May 10 Federal Register notice, the U.S. Food and Drug Administration (FDA) announced availability of final guidance on the benefits and limitations of the use of microsampling techniques in toxicokinetics studies. Benefits of these techniques include reducing the numbers of animals needed for these studies.
The National Institute of Environmental Health Sciences (NIEHS) Superfund Research Program is hosting a webinar series highlighting research that may be useful as new approaches and methodologies for toxicity testing. This series coincides with recent initiatives found in the EPA draft strategic plan discussed above and the Strategic Roadmap for Establishing New Approaches to Evaluate the Safety of Chemicals and Medical Products in the United States.
NICEATM requests available data and information on approaches and/or technologies currently used for identifying potential developmental toxicants. Submitted information will be used to assess the state of the science and determine technical needs for non-animal test methods used to evaluate the potential of chemicals to induce adverse effects in offspring.
The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) asks all stakeholders to complete a survey on the use of complex in vitro models and how they should best be validated until May 31, 2018.
The Japanese Ministry of Agriculture, Forestry and Fisheries decided on March 30 to no longer require the chronic toxicity test on dogs for pesticide risk assessment according to the Humane Society International (HSI).
The U.S. Environmental Protection Agency has released a draft science policy to reduce the use of animals in testing chemicals to evaluate whether they cause an allergic reaction, inflammation or sensitization of the skin. The draft policy is open for public comment until June 9, 2018.
The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a global study aiming to provide an overview of education and training opportunities offered at high school, university and professional levels.
The prize was awarded to Dr Elisa Passini and colleagues from the University of Oxford and Janssen Pharmaceutica for developing an in silico model to predict the potential of drugs to cause heart arrhythmia.
The German society Ärzte gegen Tierversuche (Doctors Against Animal Experiments Germany) has compiled an incomplete list of research money dedicated to animal experiments or to 3Rs research in Germany.