Latest Articles

Latest Articles

Latest Articles are manuscripts that have recently been accepted for publication in ALTEX but have not yet undergone editing, layout, and proofreading. They are replaced by a final version with the same doi upon print publication in an issue of ALTEX.

In vitro-based prediction of human plasma concentrations of food-related compounds

Takashi Kitaguchi, Mina Ito, Katsutoshi Ohno, Noriaki Ota, Kazuhiro Kobayashi, Hiromi Sato, Takahiro Iwao, Tamihide Matsunaga, Mitsuru Tanaka, Akihiro Hisaka
Published: May 12, 2023

Comparing translational success rates across medical research fields

A combined analysis of literature and clinical trial data

Gwen Van de Wall, Astrid van Hattem, Joy Timmermans, Merel Ritskes-Hoitinga, André Bleich, Cathalijn Leenaars
Published: May 5, 2023

A human iPSC-based in vitro neural network formation assay to investigate neurodevelopmental toxicity of pesticides

Kristina Bartmann, Farina Bendt, Arif Dönmez, Daniel Haag, H. Eike Keßel, Stefan Masjosthusmann, Christopher Noel, Ji Wu, Peng Zhou, Ellen Fritsche
Published: May 3, 2023

Applying a next generation risk assessment framework for skin sensitisation to inconsistent new approach methodology information

Nicola Gilmour, Nathalie Alépée, Sebastian Hoffmann, Petra Kern, Erwin Van Vliet, Dagmar Bury, Masaaki Miyazawa, Hayato Nishida, Cosmetics Europe
Published: Mar 14, 2023

Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration

Patricia L. Bishop, Susy Brescia, Rachel Brunner, Warren Casey, Kathleen Conlee-Griffin, Richard A. Currie, Jeanne Domoradzki, Michelle Embry, Maria Ines Harris, Thomas Hartung, Gina M. Hilton, Barry Hooberman, Brandall Ingle, Kyung-Jin Jang, Lewis Kinter, Caroline Krall, Joseph Leedale, Anna Lowit, Jyotigna Mehta, Elizabeth Mendez, Bob Mingoia, Eliana Munarriz, Lynea Murphy, Angela Myer, Antoniana Ottoni, Martina Panzarea, Monique Perron, Juan Pina, Deborah Ramsingh, Fiona Sewell, Jennifer Swanson, Yu-Mei Tan, Andrea Terron, Maria A. Trainer, Marize Campos Valadares, Steven Webb, Elizabeth Webb, Catherine Willett, Douglas C. Wolf
Published: Mar 8, 2023

Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment

Jan Turner, Pandora Pound, Carla Owen, Isobel Hutchinson, Marina Hop, David Y. S. Chau, Lady V. Barrios Silva, Mike Coleman, Audrey Dubourg, Lorna W. Harries, Victoria Hutter, J- Gerry Kenna, Volker M. Lauschke, Winfried Neuhaus, Clive Roper, Paul B. Watkins, Jonathan Welch, Laura R. Alvarez, Katy Taylor
Published: Jan 18, 2023

Applications of microphysiological systems to disease models in the biopharmaceutical industry: Opportunities and challenges

Onyi Irrechukwu, Ronnie Yeager, Rhiannon David, Jason Ekert, Anitha Saravanakumar, Colin K. Choi
Published: Jan 12, 2023

The GARD™skin assay: Investigation of the applicability domain for metals

Andy Forreryd, Robin Gradin, Olivia Larne, Nissanka Rajapakse, Eliot Deag, Henrik Johansson
Published: Nov 3, 2022

Proceedings of a workshop to address animal methods bias in scientific publishing

Catharine E. Krebs, Celean Camp, Helder Constantino, Lilas Courtot, Owen Kavanagh, Sofia Batista Leite, Judith Madden, Alicia Paini, Brinda Poojary, Ignacio J. Tripodi, Emily R. Trunnell
Published: Oct 31, 2022