Latest Articles

Latest Articles are manuscripts that have recently been accepted for publication in ALTEX but have not yet undergone editing, layout, and proofreading. They are replaced by a final version with the same doi upon print publication in an issue of ALTEX.

Refining humane endpoints in mouse models of disease by systematic review and machine learning-based endpoint definition

Jie Mei, Stefanie Banneke, Janet Lips, Melanie T. C. Kuffner, Christian J. Hoffmann, Ulrich Dirnagl, Matthias Endres, Christoph Harms, Julius V. Emmrich

DOI: https://doi.org/10.14573/altex.1812231

Published: Apr 18, 2019

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Activation of TRPA1 by volatile organic chemicals leading to sensory irritation

Jeanelle M. Martinez, Thomas E. Eling

DOI: https://doi.org/10.14573/altex.1811012

Published: Apr 18, 2019

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The impact of precision uncertainty on predictive accuracy metrics of non-animal testing methods

Maria Leontaridou, Silke Gabbert, Robert Landsiedel

DOI: https://doi.org/10.14573/altex.1810111

Published: Apr 5, 2019

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Opportunities for refinement in neuroscience: Indicators of wellness and post-operative pain in laboratory macaques

Kris A. Descovich, Susan E. Richmond, Matthew C. Leach, Hannah M. Buchanan-Smith, Paul Flecknell, David A. H. Farningham, Claire Witham, M. Carolyn Gates, Sarah-Jane Vick

DOI: https://doi.org/10.14573/altex.1811061

Published: Mar 29, 2019

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Insights into in vitro biokinetics using Virtual Cell Based Assay simulations

Susana Proença, Alicia Paini, Elisabeth Joossens, Jose Vicente Sala Benito, Elisabet Berggren, Andrew Worth, Maurice Whelan, Pilar Prieto

DOI: https://doi.org/10.14573/altex.1812101

Published: Mar 28, 2019

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Presence of vasculature results in faster insulin response in adipocytes in vascularized adipose tissue model

Outi Huttala, Jertta-Riina Sarkanen, Tuula Heinonen, Timo Ylikomi

DOI: https://doi.org/10.14573/altex.1811271

Published: Mar 15, 2019

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Comparison of in chemico skin sensitization methods and development of an in chemico skin photosensitization assay

Nitin H. Patel, Priyanka K. Mishra, Rajendra Nagane, Abhay Deshpande, Irfan Y. Tamboli, Rahul Date

DOI: https://doi.org/10.14573/altex.1811011

Published: Mar 11, 2019

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An in vitro coculture system for the detection of sensitization following aerosol exposure

Aline Chary, Tommaso Serchi, Elisa Moschini, Jennifer Hennen, Sebastien Cambier, Janine Ezendam, Brunhilde Blömeke, Arno C. Gutleb

DOI: https://doi.org/10.14573/altex.1901241

Published: Feb 20, 2019

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How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models

Diego Marescotti, Tommaso Serchi, Karsta Luettich, Yang Xiang, Elisa Moschini, Marja Talikka, Florian Martin, Karine Baumer, Remi Dulize, Dariusz Peric, David Bornand, Emmanuel Guedj, Alain Sewer, Sebastian Cambier, Servane Contal, Aline Chary, Arno C. Gutleb, Stefan Frentzel, Nikoloai V. Ivanov, Manuel C. Peitsch, Julia Hoeng

DOI: https://doi.org/10.14573/altex.1811221

Published: Feb 12, 2019

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