Editorial

85

Food for thought … on alternative methods for nanoparticle safety testing

87-95

Investigation of bone allografts representing different steps of the bone bank procedure via the CAM-model

97-103

Pancreatic beta cell lines and their applications in diabetes mellitus research

105-113

Calling on science: making “alternatives” the new gold standard

135-143

The principles of humane experimental technique: timeless insights and unheeded warnings

144-148

The principles of humane experimental technique: Is it relevant today?

149-151

Brueghel’s two monkeys: passing the final exam in the history of mankind

152-158

The Botulinum neurotoxin LD50 test – problems and solutions

114-116

Implementation and enforcement of the 3Rs principle in the field of transgenic animals used for scientific purposes. Report and recommendations of the BfR expert workshop, May 18-20, 2009, Berlin, Germany

117-134

Konstanz/Germany: Inauguration of CAAT-EU – a memorable start to a transatlantic collaboration

159-160

Brussels/Belgium: EPAA reinforces action on dissemination

161-163

Bad Boll/Germany: Animal suffering and distress – what are the limits of ethical defensibility?

163-164

News

165-172

Calendar

104

Imprint

U3

Instructions to authors

96

Cover