Editorial

Sonja von Aulock

U2

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Food for Thought ...

Evidence-based absorption, distribution, metabolism, excretion (ADME) and its interplay with alternative toxicity methods

Katya Tsaioun, Bas J. Blaauboer, Thomas Hartung

343-358

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Articles

International regulatory needs for development of an IATA for non-genotoxic carcinogenic chemical substances

Miriam N. Jacobs, Annamaria Colacci, Kimmo Louekari, Mirjam Luijten, Betty C. Hakkert, Martin Paparella, Paule Vasseur

359-392

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Ex vivo assessment of testicular toxicity induced by carbendazim and iprodione, alone or in a mixture

Cédric Pisani, Sébastien Voisin, Karim Arafah, Philippe Durand, Marie-Hélène Perrard, Marie-Roberte Guichaoua, Philippe Bulet, Odette Prat

393-413

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A first vascularized skin equivalent as an alternative to animal experimentation

Florian Groeber, Lisa Engelhardt, Julia Lange, Szymon Kurdyn, Freia F. Schmid, Christoph Rücker, Stephan Mielke, Heike Walles, Jan Hansmann

415-422

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MUTZ-3 Langerhans cell maturation and CXCL12 independent migration in reconstructed human gingiva

Ilona J. Kosten, Sander W. Spiekstra, Tanja D. de Gruijl, Susan Gibbs

423-434

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Advancing toxicology research using in vivo high throughput toxicology with small fish models

Antonio Planchart, Carolyn J. Mattingly, David Allen, Patricia Ceger, Warren Casey, David Hinton, Jyotshna Kanungo, Seth W. Kullman, Tamara Tal, Maria Bondesson, Shawn M. Burgess, Con Sullivan, Carol Kim, Mamta Behl, Stephanie Padilla, David M. Reif, Robert L. Tanguay, Jon Hamm

435-452

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Short communications

Bridging the gap between regulatory acceptance and industry use of non-animal methods

Amy J. Clippinger, Erin Hill, Rodger Curren, Patricia Bishop

453-458

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Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies

Joaquín Valdés, Laura Trachsel-Moncho, Ayse Sahaboglu, Dragana Trifunović, María Miranda, Marius Ueffing, François Paquet-Durand, Oliver Schmachtenberg

459-464

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Letters

EU statistics on animal experiments for 2014

Katy Taylor, Laura Rego

465-468

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Meeting Reports

Futuristic approach to alternatives

Mohammad A. Akbarsha, Abhijit Majumder, Namita Misra, Christian Pellevoisin, Jose Cotovio

469-470

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New alternative models for in vitro toxicology

Francesca Caloni, Marisa Meloni, Yula Sambuy, Susanna Alloisio, Giovanna Mazzoleni

470-471

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Corners

472-478

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News

479-483

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Calendar

414

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Imprint

484

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Cover

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