Editorial

Editorial

Sonja von Aulock

1

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Food for Thought ...

Food for thought … on alternative methods for chemical safety testing

Thomas Hartung

3-14

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Review and report series of t4 – the transatlantic think tank for toxicology

Franz P. Gruber

15

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Articles

First alternative method validated by a retrospective weight-of-evidence approach to replace the Draize eye test for the identification of non-irritant substances for a defined applicability domain

Thomas Hartung, Leon Bruner, Rodger Curren, Chantra Eskes, Alan Goldberg, Pauline McNamee, Laurie Scott, Valérie Zuang

43-51

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The serum-free media interactive online database

Daniel Brunner, Jürgen Frank, Helmut Appl, Harald Schöffl, Walter Pfaller, Gerhard Gstraunthaler

53-62

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The Center for Alternatives to Animal Testing – Europe (CAAT-EU): a transatlantic bridge for the paradigm shift in toxicology

Mardas Daneshian, Marcel Leist, Thomas Hartung

63-69

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Markers of murine embryonic and neural stem cells, neurons and astrocytes: Reference points for developmental neurotoxicity testing

Philipp B. Kuegler, Bastian Zimmer, Tanja Waldmann, Birte Baudis, Sten Ilmjärv, Jürgen Hescheler, Phil Gaughwin, Patrik Brundin, William Mundy, Anna K. Bal-Price, André Schrattenholz, Karl-Heinz Krause, Christoph van Thriel, Mahendra S. Rao, Suzanne Kadereit, Marcel Leist

16-42

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Letters

Open letter to the German Chancellor Dr. Angela Merkel

Kurt W. Simons

70-73

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Meeting Reports

Copenhagen: Improving in vitro methods by developing and using defined culture media

Jan van der Valk, Maria Laura Scarino, Lisbeth Knudsen, Gerhard Gstraunthaler

74-75

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Ethiopia: Alternatives in life science education at Ambo University

Goran Krummenacher

75

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News

News

Franz P. Gruber

76-83

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Calendar

Calendar

Franz P. Gruber

84

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Imprint

Imprint

Franz P. Gruber

U3

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Instructions to authors

Franz P. Gruber

52

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Cover

Cover

Franz P. Gruber
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