Practical workshop on replacing fetal bovine serum (FBS) in life science research: From theory into practice
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Brischwein, M. and Wiest, J. (2018). Microphysiometry. In F. Matysik and J. Wegener (eds.), Bioanalytical Reviews (163-188). Berlin Heidelberg: Springer.
Cassotta, M., Pistollato, F., Bartnicka, J. J. et al. (2021). A survey on the use of animal derived materials and reagents in scientific experimentation. ALTEX Proc 9, 352-353. https://proceedings.altex.org/data/2021-01/altex_WC11.pdf
Cassotta, M., Pistollato, F., Bartnicka, J. J. et al. (2022). A worldwide survey on the use of animal-derived materials and reagents in scientific experimentation. Eng Life Sci 22, 564–583. doi:10.1002/elsc.202100167
Gstraunthaler, G., Lindl, T. and van der Valk, J. (2013). A plea to reduce or replace fetal bovine serum in cell culture media. Cytotechnology 65, 791-793. doi:10.1007/s10616-013-9633-8
Hayashi, I. and Sato, G. (1976). Replacement of serum by hormones permits growth of cells in a defined medium. Nature 259, 132-134. doi:10.1038/259132a0
Hodgson, J. (1991). Checking sources: The serum supply secret. Biotechnology 9, 1320-1324. doi:10.1038/nbt1291-1320
Hodgson, J. (1993). Fetal bovine serum revisited. Nature Biotechnology 11, 49-53. doi:10.1038/nbt0193-49
Jochems, C. E. A., van der Valk, J. B. F., Stafleu, F. R. et al. (2002). The use of fetal bovine serum: Ethical or scientific problem? Altern Lab Anim 30, 219-227. doi:10.1177/026119290203000208
van der Valk, J., Brunner, D., de Smet, K. et al. (2010). Optimization of chemically defined cell culture media – Replacing fetal bovine serum in mammalian in vitro methods. Toxicol In Vitro 24, 1053-1063. doi:10.1016/j.tiv.2010.03.016
van der Valk, J., Bieback, K., Buta, C. et al. (2018). Fetal bovine serum (FBS): Past – present – future. ALTEX 35, 99-118. doi:10.14573/altex.1705101
van der Valk, J. (2022). Fetal bovine serum – A cell culture dilemma. Science 375, 143-144. doi:10.1126/science.abm1317
Weber, T. and Wagner, K. (2021). Replacing fetal bovine serum (FBS) in research and testing. ALTEX 38, 163-164. doi:10.14573/altex.2012141
Weber, T., Wirths, F., Brakebusch, N. et al. (2021). Reply to comment “Animal welfare and ethics in the collection of fetal blood for the production of fetal bovine serum.” ALTEX 38, 324-326. doi:10.14573/altex.2103191
Weber, T., Wiest, J., Oredsson, S. et al. (2022). Case studies exemplifying the transition to animal component-free cell culture. Altern Lab Anim 50, 330-338. doi:10.1177/02611929221117999