Editorial

Sonja von Aulock

U2

New European Union statistics on laboratory animal use – what really counts!

Francois Busquet, Andre Kleensang, Costanza Rovida, Kathrin Herrmann, Marcel Leist, Thomas Hartung

167-186

A rational approach of early humane endpoint determination in a murine model for cholestasis

Xianbin Zhang, Simone Kumstel, Guanglin Tang, Steven R. Talbot, Nico Seume, Kerstin Abshagen, Brigitte Vollmar, Dietmar Zechner

197-207

The value of organs-on-chip for regulatory safety assessment

Minne B. Heringa, Margriet V. D. Z. Park, Anne S. Kienhuis, Rob J. Vandebriel

208-222

Procurement and ex-situ perfusion of isolated slaughterhouse-derived livers as a model of donors after circulatory death

Daniele Dondossola, Stefano De Falco, Alessia Kersik, Marco Maggioni, Luca Di Girolamo, Osvaldo Biancolilli, Mattia Busana, Caterina Lonati, Francesco Carù, Alberto Zanella, Stefano Gatti

243-254

In vitro demonstration of intestinal absorption mechanisms of different sugars using 3D organotypic tissues in a fluidic device

Alessandra Marrella, Paolo Buratti, Jan Markus, Giuseppe Firpo, Mario Pesenti, Timothy Landry, Seyoum Ayehunie, Silvia Scaglione, Helena Kandarova, Maurizio Aiello

255-264

An advanced in vitro model to assess glaucoma onset

Sergio C. Saccà, Sara Tirendi, Sonia Scarfì, Mario Passalacqua, Francesco Oddone, Carlo E. Traverso, Stefania Vernazza, Anna M. Bassi

265-274

Safety assessment of excipients (SAFE) for orally inhaled drug products

Julia K. Metz, Lara Scharnowske, Fabian Hans, Sabrina Schnur, Katharina Knoth, Horst Zimmer, Markus Limberger, Henrik Groß, Claus-Michael Lehr, Marius Hittinger

275-286

Open access webinars bring 3R experts to your web browser: The Berlin experience

Katharina Hohlbaum, Vivian Kral, Christian Zoschke, Bernhard Hiebl, Monika Schäfer-Korting, Christa Thöne-Reineke

300-303

One year Charité 3R - Results and perspectives

Konstantina Diamantara, Ida Retter, Julia Biederlack

307-308

Increasing the use of animal-free recombinant antibodies

Katherine Groff, David Allen, Warren Casey, Amy Clippinger

309-311

EFSA – Johns Hopkins Food Safety Symposium 2019

Lisa Libowitz, Martin W. Bloem, Marta Hugas, Katya Tsaioun, Bernhard Url, Thomas Hartung

312-314

R2N Science Camp

Stevie van der Mierden, Cathalijn Leenaars, André Bleich

315-316

Non animal methodologies (NAMs): Research, testing, assessment and applications – ecopa Symposium 2019

Stefano Lorenzetti, Gabriele Aquilina, Francesca Caloni, Eliana M. Coccia, Pietro Cozzini, Gabriele Cruciani, Alexandre Fouassier, Andrea Gissi, Laura Goracci, Tuula Heinonen, Philippe Hubert, Federica Madia, Francesco Nevelli, Alberto Rainer, Costanza Rovida, Augusto Vitale, Isabella De Angelis

317-320

Corners

Sonja von Aulock

324-331

Erratum to Machine learning prediction of cyanobacterial toxin (microcystin) toxicodynamics in humans

Stefan Altaner, Sabrina Jaeger, Regina Fotler, Ivan Zemskov, Valentin Wittmann, Falk Schreiber, Daniel R. Dietrich

337-338

Advertisement

Sonja von Aulock

339

Imprint

Sonja von Aulock

340

Cover

Sonja von Aulock

U1-U4