Vol. 15 No. Supp1 (1998): 2. Paul-Ehrlich-Seminar über Tierschutzaspekte bei der Zulassung und Prüfung von immunologischen Arzneimitteln | ALTEX

Harald Klein, Martina Anduleit, Monika Bornhak, Matthias Fischer, Uwe Gross, Bettina Löschner, Sven Nicol, Ingrid Reiter-Orwona, Nadja Zyto, Thomas Montag-Lessing

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[Humane endpoints as a replacement for the estimation of lethality rates in the potency testing of rabies vaccines] [Article in German]

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[Detection of extraneous virus in live vaccines] [Article in German]

Beate Krämer, Petra Rübmann, Karin Duchow, Klaus Cussler

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[How to prove complete virus inactivation in rabies vaccines. A comparison of an in vivo to an in vitro method] [Article in German]

Stephanie A. E. Blum, Manuela Braunschweiger, Beate Krämer, Petra Rübmann, Karin Duchow, Klaus Cussler

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[Avian Enzephalomyelitis of poultry: Contribution on the reduction of animals during vaccine testing] [Article in German]

Anja Langhardt, Laura Frank, Brigitte Küchler, Carmen Jungbäck

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[Detection of Clostridium novyi type B alpha toxin using cell culture systems] [Article in German]

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[Development of a cytotoxin inhibition text for the detection of serum antibodies against the a-toxin of Clostridium septicum] [Article in German]

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[Development and prevalidation of alternative methods for the potency testing of C. perfringens vaccines] [Article in German]

Elvira Ebert, Volker Öppling, Esther Werner, Klaus Cussler

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[Development of an in vitro assay for the detection of Botulinum Neurotoxins - preliminary results] [Article in German]

Frank Gessler, Susanne Behrens, Petra Loch, Helge Böhnel

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[The establishment of endotoxin limits which satisfy animal welfare considerations in the testing of porcine vaccines] [Article in German]

Marion Wegener, Lukas Bruckner, Klaus Cussler

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[Cytokine release after administration of endotoxin containing vaccines] [Article in German]

Martina Ecker, Günter Müller

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[Evaluation of the relevance of the target animal safety test for the quality control of veterinary immunological medicinal products] [Article in German]

Angela Pößnecker, Klaus Cussler

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[Testing fish vaccines with an in vitro lymphocyte blastogenesis assay] [Article in German]

Ralf P. Pund, Katrin Nold, Elke Henrion

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[Development of an ELISA-system for the assessment of furunculosis vaccines ] [Article in German]

Ulrich Wagner, Dietlind Hädge, Ingolf Lachmann, Karl Drößler

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[A comparison of commercially available adjuvants in BALB/c-mice immunised with a weekly immunogenic peptide] [Article in German]

Christine Zwerger, Roland Plesker, Kyriakos Papadopulos, Klaus Cussler, Joachim Hartinger

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[Influence of route of injection on efficacy and side effects of immunisation] [Article in German]

P. P. A. Marlies Leenaars, Coenraad F. M. Hendriksen

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Editorial

Editorial

Articles

[AGAATI/ECVAM Workshop on the Validation of Alternative Methods for the Potency Testing of Vaccines (summary only)] [Article in German]

[Alternatives to animal experimentation. The sophisticated process of validation] [Article in German]

[Development and evaluation of a pyrogen test based on human whole blood ] [Article in German]

[First results in the prevaluation of the human whole blood assay for pyrogens in biological pharmaceuticals] [Article in German]

[A new test for the detection of pyrogens in pharmaceutical products] [Article in German]

[Development of a pyrogen test based on rabbit blood] [Article in German]

[Development of an alternative method to the monkey neurovirulence test for oral poliovirus vaccines] [Article in German]

[Alternative for the neurovirulence test (NTV) in primates for safety-testing of poliomyelitis attenuated life virus vaccine (Sabin): in vitro test MAPREC] [Article in German]

[Alternative for the neurovirulence test (NVT) in primates for safety-testing of poliomyelitis attenuated life virus vaccine (Sabin): NVT in transgenic mice] [Article in German]

[Use of in vitro correlates for selection of candidate immunosuppressive antibodies prior to a primate transplant model] [Article in German]

[Potency testing of anti-lymphocyte Globulins: In vitro alternatives for the monkey sking-graft assay] [Article in German]

[Optimisation and establishing of serological methods for the potency testing of immunglobulins against Clostridium tetani-toxin] [Article in German]

[Pertussis serological potency test as an alternative to the intracerebral mouse protection test: development, evaluation und validation] [Article in German]

[Characteristics of Toxoplasma-gondii-tachyzoites from different culture systems] [Article in German]