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Vol. 15 No. Supp1 (1998): 2. Paul-Ehrlich-Seminar über Tierschutzaspekte bei der Zulassung und Prüfung von immunologischen Arzneimitteln
Editorial
Editorial
Franz P. Gruber, Johannes Löwer, Manfred Moos
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Articles
[AGAATI/ECVAM Workshop on the Validation of Alternative Methods for the Potency Testing of Vaccines (summary only)] [Article in German]
Marlies Halder, Coenraad F. M. Hendriksen, Jean-Marc Spieser
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[Alternatives to animal experimentation. The sophisticated process of validation] [Article in German]
Michael Schwanig
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[Development and evaluation of a pyrogen test based on human whole blood ] [Article in German]
Thomas Hartung, Stefan Fennrich, Matthias Fischer, Thomas Montag-Lessing, Albrecht Wendel
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[First results in the prevaluation of the human whole blood assay for pyrogens in biological pharmaceuticals] [Article in German]
Matthias Fischer, Katja Hartzsch, Thomas Hartung, Thomas Montag-Lessing
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[A new test for the detection of pyrogens in pharmaceutical products] [Article in German]
Markus Weigandt, Peter Lexa, Hans-Günther Sonntag
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[Development of a pyrogen test based on rabbit blood] [Article in German]
Thomas Hartung, Reto Crameri, Albrecht Wendel
pdf
[Development of an alternative method to the monkey neurovirulence test for oral poliovirus vaccines] [Article in German]
Artur Kaul, Micha Nübling, Martina Kempfer, Ivo Schmidt, Johannes Löwer
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[Alternative for the neurovirulence test (NTV) in primates for safety-testing of poliomyelitis attenuated life virus vaccine (Sabin): in vitro test MAPREC] [Article in German]
Volker Dörsam, Andreas Schmeel, Konstantin Chumakov, Mathias R. Fibi
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[Alternative for the neurovirulence test (NVT) in primates for safety-testing of poliomyelitis attenuated life virus vaccine (Sabin): NVT in transgenic mice] [Article in German]
Andreas Schmeel, Mathias R. Fibi
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[Use of in vitro correlates for selection of candidate immunosuppressive antibodies prior to a primate transplant model] [Article in German]
Miriam A. Ossevoort, Maria C. Noort, Almuth Radzikowski, Yvon van der Hout, Katrien Lorré, Peter De Waele, Margreet Jonker
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[Potency testing of anti-lymphocyte Globulins: In vitro alternatives for the monkey sking-graft assay] [Article in German]
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[Optimisation and establishing of serological methods for the potency testing of immunglobulins against Clostridium tetani-toxin] [Article in German]
Elvira Ebert, Annett Abu Karim, Tanja Kayser, Renate Wenig, Karin Weißer, Maria Wirz, Giulio Pisani, Gabriele Schäffner, Klaus Cussler
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[Pertussis serological potency test as an alternative to the intracerebral mouse protection test: development, evaluation und validation] [Article in German]
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[Characteristics of Toxoplasma-gondii-tachyzoites from different culture systems] [Article in German]
Harald Klein, Martina Anduleit, Monika Bornhak, Matthias Fischer, Uwe Gross, Bettina Löschner, Sven Nicol, Ingrid Reiter-Orwona, Nadja Zyto, Thomas Montag-Lessing
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[Humane endpoints as a replacement for the estimation of lethality rates in the potency testing of rabies vaccines] [Article in German]
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[Detection of extraneous virus in live vaccines] [Article in German]
Beate Krämer, Petra Rübmann, Karin Duchow, Klaus Cussler
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[How to prove complete virus inactivation in rabies vaccines. A comparison of an in vivo to an in vitro method] [Article in German]
Stephanie A. E. Blum, Manuela Braunschweiger, Beate Krämer, Petra Rübmann, Karin Duchow, Klaus Cussler
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[Avian Enzephalomyelitis of poultry: Contribution on the reduction of animals during vaccine testing] [Article in German]
Anja Langhardt, Laura Frank, Brigitte Küchler, Carmen Jungbäck
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[Detection of Clostridium novyi type B alpha toxin using cell culture systems] [Article in German]
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[Development of a cytotoxin inhibition text for the detection of serum antibodies against the a-toxin of Clostridium septicum] [Article in German]
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[Development and prevalidation of alternative methods for the potency testing of C. perfringens vaccines] [Article in German]
Elvira Ebert, Volker Öppling, Esther Werner, Klaus Cussler
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[Development of an in vitro assay for the detection of Botulinum Neurotoxins - preliminary results] [Article in German]
Frank Gessler, Susanne Behrens, Petra Loch, Helge Böhnel
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[The establishment of endotoxin limits which satisfy animal welfare considerations in the testing of porcine vaccines] [Article in German]
Marion Wegener, Lukas Bruckner, Klaus Cussler
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[Cytokine release after administration of endotoxin containing vaccines] [Article in German]
Martina Ecker, Günter Müller
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[Evaluation of the relevance of the target animal safety test for the quality control of veterinary immunological medicinal products] [Article in German]
Angela Pößnecker, Klaus Cussler
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[Testing fish vaccines with an in vitro lymphocyte blastogenesis assay] [Article in German]
Ralf P. Pund, Katrin Nold, Elke Henrion
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[Development of an ELISA-system for the assessment of furunculosis vaccines ] [Article in German]
Ulrich Wagner, Dietlind Hädge, Ingolf Lachmann, Karl Drößler
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[A comparison of commercially available adjuvants in BALB/c-mice immunised with a weekly immunogenic peptide] [Article in German]
Christine Zwerger, Roland Plesker, Kyriakos Papadopulos, Klaus Cussler, Joachim Hartinger
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[Influence of route of injection on efficacy and side effects of immunisation] [Article in German]
P. P. A. Marlies Leenaars, Coenraad F. M. Hendriksen
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Imprint
Imprint
Franz P. Gruber
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Cover
Cover
Franz P. Gruber
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